Results 131 to 140 of about 124,338 (379)

Non‐thermal plasma decontamination of microbes: a state of the art

Biotechnology Progress, Volume 41, Issue 2, March/April 2025.
Abstract Microbial decontamination is a critical concern in various sectors, from healthcare to food processing. Traditional decontamination methods, while effective to a degree, present limitations in terms of environmental impact, efficiency, and potential harm to the target material. This review investigates the emerging realm of non‐thermal plasma (
Yiyi Xu, Amarjeet Bassi
wiley   +1 more source

Thymidine Phosphorylase Inhibitory Potential and Molecular Docking Studies of Secondary Metabolites Isolated From Fernandoa adenophylla (Wall. ex G. Don) Steenis

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigates the potential of Fernandoa adenophylla, a South American plant, as a reservoir of compounds with thymidine phosphorylase (TP) inhibitory activity. Through a comprehensive approach combining in vitro assays and molecular docking analysis, we isolated and characterized bioactive compounds from F.
Abdur Rauf, Majid Khan, Umer Rashid, Anees Saeed, Zafar Ali Shah, Zubair Ahmad, Abdulhakeem S. Alamri, Walaa F. Alsanie, Imtiaz Khan, Humaira Hussain, Majid Alhomrani, Marcello Iriti   +11 more
wiley   +1 more source

The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA [PDF]

, 1968
In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during ...
Knippers, Rolf, Komano, Tohru, Sinsheimer, Robert L.   +2 more
core  

Laser flash photolysis and magnetic-field-effect studies on interaction of thymine and thymidine with menadione: role of sugar in controlling reaction pattern

Science and Technology of Advanced Materials, 2008
The magnetic field effect (MFE) in conjunction with laser flash photolysis has been used for the study of the interaction of one of the small drug like quinone molecules, 2-methyl, 1,4-naphthoquinone, commonly known as menadione (MQ), with one of the DNA
Adity Bose, Debarati Dey and Samita Basu
doaj  

γ-PNA PREORGANIZATION: SYNTHESIS OF MODEL DIMER AND ITS STRUCTURE STUDY BY 2D NMR SPECTROSCOPY

Тонкие химические технологии, 2017
The synthesis of a dimer consisting of γ-thymine chiral monomer based on L-Ala and thymine aeg-PNA monomer (synthesized from deuterated glycine), in which the methylene protons of the pseudopeptide residue were exchanged with deuterium atoms, was ...
A. V. Dezhenkov, D. A. Cheshkov, I. A. Prokhorov, A. I. Lutik, Yu. G. Kirillova   +4 more
doaj   +1 more source

Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP‐Lyase Function

Chemistry – A European Journal, EarlyView.
Organocatalytic switches are small molecules that combine active site affinity and a nitrogen‐centered base for catalysis, effectively removing the rate‐determining step of the OGG1 biochemical cascade. Here, we identify a minimal structure and modulate the active nitrogen pKa, enabling the catalysis of ultrafast AP site incisions in a range of pH ...
Mario Kehler, Kaixin Zhou, Aurino M. Kemas, Alicia del Prado, Emma Scaletti Hutchinson, Elinor Hesslefors Nairn, Marek Varga, Yvonne Plattner, Yi Zhong, Oryn Purewal‐Sidhu, James Haslam, Elisée Wiita, Heather Gildie, Karolina Singerova, Zuzanna Szaruga, Ingrid Almlöf, Femke M. Hormann, Kang‐Cheng Liu, Olov Wallner, Florian Ortis, Evert J. Homan, Opher Gileadi, Sean G. Rudd, Pål Stenmark, Miguel de Vega, Thomas Helleday, Nicholas D. D'Arcy‐Evans, Volker M. Lauschke, Maurice Michel   +28 more
wiley   +1 more source

Fully Supramolecular Polyrotaxanes as Biphase Drug Delivery Systems

International Journal of Polymer Science, 2014
Pseudopolyrotaxanes (PPR) consisting of α-cyclodextrin rings and polyethylene glycol axes with end thymine groups have been synthesized and characterized successfully.
Abdolhossien Massoudi, Mohsen Adeli, Leila Khosravi far   +2 more
doaj   +1 more source

Uso da 99mTc-Timina na identificação de metástases de tumor venéreo transmissível canino com apresentação cutânea The use of 99mTc-Thymine to identify metastatic disease in dogs presenting the cutaneous form of canine transmissible venereal tumor

Pesquisa Veterinária Brasileira, 2008
O tumor venéreo transmissível canino (TVTC) é descrito na literatura como raramente metastático. Entretanto, métodos acurados para verificação dessa afirmativa não estão disponíveis na rotina veterinária.
Paulo S.M. Castelo-Branco, Sergio A. Lopes de Souza, Flávia P.P. Lobo Lopes, Verônica Castro, Priscila Sena, João Batista Pereira, Lea M. Barbosa da Fonseca, Bianca Gutfilen   +7 more
doaj   +1 more source

The Symmetry of the Genetic Code and a Universal Trend of Amino Acid Gain and Loss [PDF]

arXiv, 2007
Part 1 of the study intends to show that the universal trend of amino acid gain and loss discovered by Jordan et al. (2005) can be accounted for by the spontaneity of DNA typical damages. These damages lead to replacements of guanine and cytosine by thymine.
arxiv  

Exploring the Modulation of the Complex Folding Landscape of Human Telomeric DNA by a Low Molecular Weight Ligand

Chemistry – A European Journal, EarlyView.
Time‐resolved nuclear magnetic resonance (NMR) and circular dichroism (CD) spectroscopy were utilized to investigate the complex G‐quadruplex folding landscape of the human telomeric DNA in the presence of the ligand Phen‐DC3. Our findings revealed significant differences in the kinetics of the pathways originating from the unfolded or K+‐bound state ...
Ines Burkhart, Julia Wirmer‐Bartoschek, Janez Plavec, Harald Schwalbe   +3 more
wiley   +1 more source