1,3-Bis(2-oxopropyl)thymine [PDF]
IUCrData, 2020 In the title compound [systematic name: 5-methyl-1,3-bis(2-oxopropyl)pyrimidine-2,4(1H,3H)-dione], C11H14N2O4, the two 2-oxopropyl groups are nearly perpendicular to the planar thymine unit. One methyl group of oxopropyl substituent is disordered. In the
Bogdan Doboszewski +2 more
doaj +2 more sources
A thymine-challenge test to prospectively evaluate dihydropyrimidine dehydrogenase activity for risk of severe 5-fluorouracil-induced gastrointestinal toxicity. [PDF]
Cancer Chemother PharmacolHelsby N +13 more
europepmc +3 more sources
Mutagenicity of a unique thymine-thymine dimer or thymine-thymine pyrimidine pyrimidone (6-4) photoproduct in mammalian cells [PDF]
Nucleic Acids Research, 1996 The mutagenic properties of UV-induced photoproducts, both the cis-syn thymine-thymine dimer (TT) and the thymine-thymine pyrimidine pyrimidone (6-4) photoproduct [T(6-4)T] were studied in mammalian cells using shuttle vectors. A shuttle vector able to replicate in both mammalian cells and bacteria was produced in its single-stranded DNA form. A unique
A, Gentil +5 more
openaire +2 more sources
Investigation of the spin-forbidden process in thymine [PDF]
Hemijska Industrija, 2012 The intersystem crossing rate from the lowest singlet to the lowest triplet state of thymine was studied by means of the ab initio methods. The rate was calculated employing the time-dependent approach based on the correlation function.
Etinski Mihajlo R.
doaj +1 more source
Synthesis of new dipeptides based on uracil and thymine and investigation of the molecular docking of these compounds as inhibitors of quorum sensing system in Pseudomonas aeruginosa [PDF]
شیمی کاربردی روز, 2019 In this study, due to the importance of dipeptide compounds in diagnosis of disease or as drug compounds, new dipeptide compounds were synthesized using pyrimidine derivatives of thymine and uracil.
Azam Heidari +3 more
doaj +1 more source
Nanomaterials, 2017 Mercury ion (Hg2+) is recognized as one of the most toxic metal ions for the environment and for human health. Techniques utilized in the detection of Hg2+ are an important factor.
Hao Yang +8 more
doaj +1 more source
Molecules, 2016 The present study provides new insights into the topography of the potential energy hypersurfaces (PEHs) of the thymine nucleobase in order to rationalize its main ultrafast photochemical decay paths by employing two methodologies based on the complete ...
Javier Segarra-Martí +3 more
doaj +1 more source
Photochemistry of Thymine in Protic Polar Nanomeric Droplets Using Electrostatic Embeding TD-DFT/MM
Molecules, 2021 Thymine photochemistry is important for understanding DNA photodamage. In the gas phase, thymine undergoes a fast non-radiative decay from S2 to S1. In the S1 state, it gets trapped for several picoseconds until returning to the ground-state S0. Here, we
Miquel Huix-Rotllant
doaj +1 more source
Molecules, 2019 The clinically widely-used anticancer drug, cisplatin, binds strongly to DNA as a DNA-damaging agent. Herein, we investigated the interaction of cisplatin with a 15-mer single-stranded C,T-rich oligodeoxynucleotide, 5′-CCTT4CTT7G8C9T10TCTCC-3′
Wenjuan Zeng +9 more
doaj +1 more source
EFFECT OF PLANT DENSITY AND FOLIAR APPLICATION WITH THYMINE IN GROWTH, YIELD AND ITS QUALITY OF FOUR BROAD BEAN GENOTYPES [PDF]
مجلة الأنبار للعلوم الزراعية, 2019 A field experiment was conducted in one of the agricultural fields in the area of Zouayt, Sityih, Ramadi, Anbar province during the winter seasons of 2017 and 2018. The region of growth traits in some genotypes deferent for faba bean.
A. M. Halil, A. M. Ali
doaj +1 more source