Results 221 to 230 of about 74,896 (329)

Unlocking atom-specific radiotherapy - DNA backbone breakage caused by X-ray photoactivation. [PDF]

open access: yesChem Sci
Svensson PHW   +15 more
europepmc   +1 more source

Force fields matter in DNA pol η$$ \eta $$ mechanistic analysis

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract DNA polymerase η$$ \eta $$ is of major interest due to debates regarding the role of a third non‐canonical magnesium ion in catalysis. By examining molecular simulations motivated by this mechanistic question and the role of the S113A mutation, we investigate how modern classical force fields compare for treating protein‐DNA complexes and ...
Reilly Osadchey, Qiang Cui
wiley   +1 more source

Updates to the CASP Infrastructure in 2024

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 15-24, January 2026.
ABSTRACT CASP (critical assessment of structure prediction) conducts community experiments to determine the state of the art in calculating macromolecular structures. The CASP data management system is continually evolving to address the changing needs of the experiments.
Andriy Kryshtafovych   +6 more
wiley   +1 more source

Helical aromatic oligoamide foldamers as selective G-quadruplex ligands. [PDF]

open access: yesNucleic Acids Res
König A   +7 more
europepmc   +1 more source

High‐Throughput Fabrication of Zero‐Mode Waveguide Nanoaperture Arrays with Sol‐Gel Nanoimprint Lithography for Enhanced Single Molecule Fluorescence Detection

open access: yesSmall, Volume 22, Issue 2, 8 January 2026.
The researchers developed a scalable and cost‐effective method to fabricate zero‐mode waveguide (ZMW) nanoapertures in metallic films using sol‐gel nanoimprint lithography and vapor‐phase etching. These nanostructures confine light to attoliter volumes, enhancing fluorescence brightness and enabling single‐molecule detection at micromolar ...
Hamza Khelidj   +6 more
wiley   +1 more source

Activation of bacterial transcription by distortion of promoter base pairing. [PDF]

open access: yesNucleic Acids Res
Klimova KM   +4 more
europepmc   +1 more source

Design, Mechanisms, and Applications of DNA‐Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
This review provides key principles of designing and synthesizing reconfigurable plasmonic gold nanostructures for generating and controlling physical, chemical, and biological properties and functions. The recent advances in the biological and materials applications of dynamically reconfigurable plasmonic gold nanostructures are also summarized ...
So Young Choi   +6 more
wiley   +1 more source

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