Results 41 to 50 of about 124,338 (379)

Observation of Ultrafast Intersystem Crossing in Thymine by Extreme Ultraviolet Time-resolved Photoelectron Spectroscopy.

Journal of Physical Chemistry A, 2019
We studied the photoinduced ultrafast relaxation dynamics of the nucleobase thymine using gas-phase time-resolved photoelectron spectroscopy. By employing extreme ultraviolet pulses from high harmonic generation for photoionization, we substantially ...
T. Wolf, R. Parrish, R. H. Myhre, T. Martínez, H. Koch, M. Gühr   +5 more
semanticscholar   +1 more source

Stabilities of nanohydrated thymine radical cations: insights from multiphoton ionization experiments and ab initio calculations [PDF]

, 2017
Multi-photon ionization experiments have been carried out on thymine-water clusters in the gas phase. Metastable H2O loss from T+(H2O)n was observed at n ≥ 3 only.
A. Golan, A.M. Rasmussen, B. Barc, B. Barc, D.M. Close, D.M. Close, E. Bruzzi, H. Kang, H.W. Jochims, I. Hunig, J. González-Vázquez, J. Jose Serrano-Perez, J.C. Lopez, J.C. Lopez, Jean-Christophe Poully, K. Khistyaev, K. Khistyaev, K.E. Riley, K.W. Choi, L. Belau, M. Etinski, M. Kabelác, M. Ligare, M. Liu, M. Ryszka, Mathieu Lalande, Michal Ryszka, N.J. Kim, N.J. Kim, N.S. Hush, Nigel J. Mason, O. Dopfer, P. Colarusso, Paulo Limão-Vieira, R. Mota, R.E. Continetti, R.H. Duncan Lyngdoh, Rahul Pandey, S. Heinbuch, S. Ishiuchi, S. Kim, S. Kim, S.K. Kim, Samuel Eden, V. Vizcaino, V.G. Stavros, Y. Ibrahim, Y. Nosenko, Y.G. He   +48 more
core   +3 more sources

Using thymine-18 for enhancing dose delivery and localizing the Bragg peak in proton-beam therapy [PDF]

arXiv, 2021
Therapeutic protons acting on O18-substituted thymidine increase cytotoxicity in radio-resistant human cancer cells. We consider here the physics behind the irradiation during proton beam therapy and diagnosis using O18-enriched thymine in DNA, with attention to the effect of the presence of thymine-18 on cancer cell death.
arxiv  

Transient Resonant Auger-Meitner Spectra of Photoexcited Thymine [PDF]

, 2020
We present the first investigation of excited state dynamics by resonant Auger-Meitner spectroscopy (also known as resonant Auger spectroscopy) using the nucleobase thymine as an example. Thymine is photoexcited in the UV and probed with X-ray photon energies at and below the oxygen K-edge.
arxiv   +1 more source

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]

, 2003
Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Cooper, M.A., Hickman, D.T., King, Paul M., Micklefield, J., Morral, J., Tan, T.H.S.   +5 more
core   +1 more source

Studies on the Two Thymine Residues in the Catalytic Core of 10-23 DNAzyme: The Impact on the Catalysis of Their 5-Substituted Functional Groups

Molecules, 2017
In the 15-mer catalytic core of 10-23 DNAzyme, each residue contributes to the catalytic conformation differently. Here, the critically conserved T4 and the least conserved T8 were modified on their 5-position with hydroxyl, imidazolyl, and amino groups ...
Pengyu Li, Shanshan Du, Yang Li, Junlin He   +3 more
doaj   +1 more source

Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling

Scientific Reports, 2019
Ru(II)-thymine complex [Ru(PPh3)2(Thy)(bipy)]PF6 (where PPh3 = triphenylphosphine, Thy = thyminate and bipy = 2,2′-bipyridine) is a potent cytotoxic agent with ability to bind to DNA, inducing caspase-mediated apoptosis in leukemia cells.
Suellen L. R. Silva, I. R. Baliza, R. Dias, C. B. Sales, C. Rocha, M. Soares, R. Corrêa, A. Batista, D. Bezerra   +8 more
semanticscholar   +1 more source

Thymine functionalised porphyrins, synthesis and heteromolecular surface-based self-assembly [PDF]

, 2014
The synthesis and surface-based self-assembly of thymine-functionalised porphyrins is described. Reaction of 1-formylphenyl-3-benzoyl-thymine with suitable pyrollic species leads to the formation of tetra-(phenylthymine)porphyrin (tetra-TP) or mono ...
Bartels, Barth, Barth, Bisson, Bisson, Blunt, Blunt, Blunt, Böhringer, Chatterjee, Chatterjee, Chen, Chen, Choi, Cicoira, Ciesielski, Ciesielski, Desiraju, Elemans, Elemans, Etter, Fazio, Frankel, Frieden, Griessl, Grill, Gutzler, Hamblin, Hoogsteen, Hosseini, Jacobsen, Katsumi, Kong, Kong, Lee, Lei, Li, Liu, Liu, Llanes-Pallas, Madueno, Maleki, Mamdouh, Mohnani, Mu, Newman, Otero, Otero, Otsuki, Otsuki, Palma, Perdigão, Radivojevic, Rao, Rao, Roelfs, Räisänen, Simard, Slater, Slater (née Phillips), Sowerby, Stepanow, Tan, Taylor, Taylor, Theobald, Vijayaraghavan, Watson, Wei, Yokoyama, Yoon, Yoshimoto, Zhang, Zhou   +73 more
core   +2 more sources

Low-energy Electron Collisions with Gas-phase Thymine Molecule

Medžiagotyra, 2011
The paper presents an investigation of the negative ion formation of the thymine (T) molecule. The formation of negative ions by electron impact of this molecule is measured.
Irina V. CHERNYSHOVA, Jeno E. KONTROS, Otto B. SHPENIK, Jelena TAMULIENE, Mindaugas L. BALEVICIUS   +4 more
doaj   +1 more source

Synthesis technique and electron beam damage study of nanometer-thin single-crystalline Thymine [PDF]

arXiv, 2023
Samples suitable for electron diffraction studies must satisfy certain characteristics such as having a thickness in the range of 10 - 100 nm. We report, to our knowledge, the first successful synthesis technique of nanometer-thin sheets of single-crystalline thymine suitable for electron diffraction and spectroscopy studies.
arxiv