Results 71 to 80 of about 124,338 (379)

Biochemical Aspects of Genetics [PDF]

open access: yes, 1965
It would be impossible, in the time and space available, to cover all of the noteworthy advances that have been made in biochemical genetics during the past year.
Horowitz, N. H., Metzenberg, Robert L.
core   +1 more source

Developing glycosylase-based T-to-G and C-to-K base editors in rice. [PDF]

open access: yesPlant Biotechnol J
Plant Biotechnology Journal, Volume 23, Issue 6, Page 2358-2360, June 2025.
Kuang Y   +7 more
europepmc   +2 more sources

Interaction of Oligonucleotides with Gold Nanoparticles: Factors Beyond Electrostatic and Van‐Der Waals Forces

open access: yesAdvanced Materials Interfaces, EarlyView.
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur   +3 more
wiley   +1 more source

A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage

open access: yesAngewandte Chemie, EarlyView.
This work advances methodology by addressing challenges in mimicking the complex in vivo spatial relationships of histone acetylation and DNA damage. The combination of an abiotic/enzymatic hybrid catalyst system (ABEHCS) and the plug‐and‐play method has constituted a versatile platform to construct nucleosome arrays with precise histone acetylation ...
Ziyun Liu   +6 more
wiley   +2 more sources

Three-Dimensional Heterocycles: New Uracil-Based Structures Obtained by Nucleophilic Substitution at the sp2 Carbon of Bromoisoxazoline

open access: yesMolecules, 2014
The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of uracil-based scaffolds. The key-synthetic step is the nucleophilic substitution at the sp2 carbon atom of
Misal Giuseppe Memeo   +3 more
doaj   +1 more source

Potential formation of three pyrimidine bases in interstellar regions [PDF]

open access: yes, 2015
Work on the chemical evolution of pre-biotic molecules remains incomplete since the major obstacle is the lack of adequate knowledge of rate coefficients of various reactions which take place in interstellar conditions. In this work, we study the possibility of forming three pyrimidine bases, namely, cytosine, uracil and thymine in interstellar regions.
arxiv   +1 more source

Exploring DNA Functionalization Techniques for Silver Nanoparticles

open access: yesAdvanced Materials Interfaces, EarlyView.
This study evaluates four functionalization methods—salt‐aging, pH‐assisted, freezing‐directed, and microwave‐assisted—for attaching DNA strands to 20 nm silver nanoparticles (AgNPs). The resulting DNA‐AgNP conjugates are characterized and colloidal stability and DNA loading are assessed.
Sebastian Freko   +3 more
wiley   +1 more source

Dissociative multi-photon ionization of isolated uracil and uracil-adenine complexes [PDF]

open access: yes, 2016
Recent multi-photon ionization (MPI) experiments on uracil revealed a fragment ion at m/z 84 that was proposed as a potential marker for ring opening in the electronically excited neutral molecule.
Barc, B.   +7 more
core   +2 more sources

Supramolecular Recognition of a DNA Four‐Way Junction by an M2L4 Metallo‐Cage, Inspired by a Simulation‐Guided Design Approach

open access: yesAngewandte Chemie, EarlyView.
DNA Holliday junctions, or four‐way junctions (4WJs) are an attractive therapeutic target due to their prevalence in DNA replication and repair, and viral disease. Combining experimental and computational methods, we show that quadruple‐stranded dinuclear platinum metallo‐cages are an excellent size and shape match for the cavity of the 4WJ open ...
Samuel J. Dettmer   +6 more
wiley   +2 more sources

Graphene-enhanced Raman spectroscopy of thymine adsorbed on single-layer graphene

open access: yesNanoscale Research Letters, 2015
Graphene-enhanced Raman scattering (GERS) spectra and coherent anti-Stokes Raman scattering (CARS) of thymine molecules adsorbed on a single-layer graphene were studied. The enhancement factor was shown to depend on the molecular groups of thymine.
O. Fesenko   +5 more
semanticscholar   +1 more source

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