A Dual‐Emissive DNA‐Templated Silver Nanocluster with Near‐Infrared I and II Emission
This study presents a dual‐emissive DNA‐stabilized silver nanocluster with a nanosecond‐lived NIR‐I emission band and a microsecond‐lived NIR‐II emission band. Mass spectrometry establishes that the nanocluster has molecular formula (DNA)2[Ag17]11+. DNA sequence variations reveal critical nucleobases for stabilization, and modifications at the DNA 5 ...
Anna Gonzàlez‐Rosell+6 more
wiley +1 more source
Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase [PDF]
hSMUG1 (human single-stranded selective monofunctional uracil-DNA glyscosylase) is one of three glycosylases encoded within a small region of human chromosome 12. Those three glycosylases, UNG (uracil-DNA glycosylase), TDG (thymine-DNA glyscosylase), and
Agus Darwanto+63 more
core +3 more sources
Beyond Structure: Methylation Fine‐Tunes Stability and Folding Kinetics of bcl2Mid G‐Quadruplex
The introduction of a single 5‐methylcytosine into a G‐rich sequence originating from the B‐cell lymphoma 2 (BCL2) gene promoter affects both the folding kinetics and thermodynamics of the two G4 structures and thus plays a crucial role in regulating G4 folding pathways, which has significant implications for the control of gene expression.
Nataša Medved+5 more
wiley +2 more sources
Thymine Incorporation and Metabolism by Various Classes of Thymine-less Bacteria [PDF]
SUMMARY: Escherichia coli strain 15T- yielded 109 organisms from 1 μg. thymine and growth was continuous, not diphasic. Aminopterin-selected thymine-less bacteria, on the other hand, required 20-25 μg. thymine/ml. to sustain growth, although thymine incorporation was the same as for strain 15T-, approximately 10-9 μg./bacterium.
openaire +3 more sources
Incorporation of Thymine into Prototrophic and Thymine-dependent Mutants of Bacillus anthracis [PDF]
SUMMARY: Mutants of Bacillus anthracis which were prototrophic in a defined medium below 32° required either thymidine (mutant thy) or low concentration of thymine (mutant thytlr) for growth at 37°. No thymidylate synthetase was produced by these mutants at 37°. Normal enzyme activity was found in bacteria grown at 25°.
Ivánovics, György+2 more
openaire +4 more sources
Vibrational Investigation of Nucleobases by Means of Divide and Conquer Semiclassical Dynamics [PDF]
In this work we report a computational study of the vibrational features of four different nucleobases employing the divide-and-conquer semiclassical initial value representation molecular dynamics method. Calculations are performed on uracil, cytosine, thymine, and adenine.
arxiv +1 more source
Self‐Assembled Physical Unclonable Function Labels Based on Plasmonic Coupling
This article introduces advanced anti‐counterfeit labels crafted through DNA‐guided self‐assembly of plasmonic nanoparticles. Utilizing nanosphere lithography for dense and precise nanoparticle placement, these labels feature unique, unclonable optical signatures achieved through plasmonic coupling, detectable by an economical 3D‐printed dark field ...
Mihir Dass+9 more
wiley +1 more source
Time-resolved photoelectron spectroscopy is performed on thymine and thymidine in aqueous solution to study the excited-state relaxation dynamics of these molecules.
Franziska Buchner+4 more
semanticscholar +1 more source
Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen+8 more
wiley +1 more source
Non-Empirically Tuned Range-Separated DFT Accurately Predicts Both Fundamental and Excitation Gaps in DNA and RNA Nucleobases [PDF]
Using a non-empirically tuned range-separated DFT approach, we study both the quasiparticle properties (HOMO-LUMO fundamental gaps) and excitation energies of DNA and RNA nucleobases (adenine, thymine, cytosine, guanine, and uracil).
Foster, Michael E., Wong, Bryan M.
core +2 more sources