Superantigens are presented by and activate thymocytes from infants.
Udgivelsesdato: 1999-nullA high percentage of human fetal and postnatal thymocytes express MHC class II molecules. This raises the possibility that human thymocytes in early life are able to present peptides to other immature T cells and thereby initiate
Dohlsten, M +6 more
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Analysis of Human Thymopoiesis Reveals Rapid Postnatal Remodeling of Thymocytes Within the First 3 Months of Life. [PDF]
Kergaravat C +10 more
europepmc +1 more source
Hematopoietic and T-lymphopoiesis-stimulating effects of a fluorinated pyrazolopiperidine β-cyclodextrin complex in cyclophosphamide-induced hematopoietic suppression. [PDF]
Ten A +6 more
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Type I IFN-controlled Qa-2 expression identifies and maps the generation of Eomes<sup>+</sup> thymic innate CD8 T cells. [PDF]
Won HY +4 more
europepmc +1 more source
Mechanisms Involved in the Binding of Thymocytes to Rat Thymic Dendritic Cells
Miodrag Čolić +4 more
doaj +1 more source
Hematopoietic Antigen Presenting Cells Fine-Tune the Effector Phenotype of Intrathymic Unconventional αβ T Cells. [PDF]
Wang Y +12 more
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Regulation of apoptosis-induction in thymocytes
Most T cells are produced in the thymus, where they proceed through several differentiation steps to shape the TCR repertoire. The first thymocyte subset to express a TCR complex is characterized by the expression of CD4 and CD8 co-receptors, CD4+CD8 ...
Lesage, Sylvie.
core
Structural characterization of PAMK and its protective effect against thymic necroptosis in goslings. [PDF]
Li W +11 more
europepmc +1 more source
Rag1-based time-stamp tracing of T-cell developmental origins. [PDF]
Jiang M +11 more
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Multifaceted regulation of thymic tolerance by pattern recognition cascades. [PDF]
Mukherjee S, Paul P, Kar A, Barik S.
europepmc +1 more source

