Results 161 to 170 of about 9,080 (213)
Improvement of antihyperglycemic activity of nano-thymoquinone in rat model of type-2 diabetes
Chemico-Biological Interactions, 2018 Thymoquinone is a bioactive constituent of Nigella sativa seeds. It has been reported to possess antihyperglycemic effect in rats. However, the effect of nanoformulation (NF) of thymoquinone has not been reported in literature.
Neeraj Dilbaghi +2 more
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Inhibition of the formation of advanced glycation end products by thymoquinone
Food Chemistry, 2011 The inhibitory activity of thymoquinone, a major quinone from black seeds (Nigella sativa) against the formation of advanced glycation end products was studied using the hemoglobin-δ-gluconolactone, human serum albumin-glucose, and the N-acetyl-glycyl ...
Jack Losso
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Structural and vibrational analysis of thymoquinone
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010The molecular structure of 2-isopropyl-5-methyl-1,4-benzoquinone, C(6)O(2)H(2) (CH(3))(3)CH, has been optimized using methods based on density functional theory (DFT) and Moller-Plesset second-order perturbation theory (MP2). As regards C(6)O(2)H(2) (CH(3))(3)CH, two populated conformations with C(1) (trans) and C(s) (cis) symmetries are obtained, the ...
A B, Raschi +4 more
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An Overview of Hepatoprotective Effects of Thymoquinone
Recent Patents on Food, Nutrition & Agriculture, 2018Liver diseases are globally recognized as major medical problems. Several species of herbal medicine have been investigated for the management of liver-related diseases.In this context, Thymoquinone (TQ) as the main constituent of Nigella sativa has long been focused for the treatment of liver diseases in recent years. To suppressing liver diseases, it
Mohammad-Foad, Noorbakhsh +4 more
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Thymoquinone: Novel gastroprotective mechanisms
European Journal of Pharmacology, 2012Ample of evidence proved the gastroprotective effect of thymoquinone (TQ), the main constituent of Nigella sativa oil; however, the full mechanistic cassette on the gastric ulcer etiopathogenesis is not fully elucidated. The aim of the present work is to unveil some of the possible mechanisms.
Mahmoud-Awny, Magdy +2 more
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Thymoquinone‐induced platelet apoptosis
Journal of Cellular Biochemistry, 2011AbstractThymoquinone (TQ) is a nutrient with anticarcinogenic activity that stimulates suicidal death of tumor cells. Moreover, TQ triggers suicidal death of erythrocytes or eryptosis, an effect at least partially due to increase in cytosolic Ca2+activity and ceramide formation.
Syeda Tasneem, Towhid +6 more
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Molecular Mechanisms of Thymoquinone as Anticancer Agent
Combinatorial Chemistry & High Throughput Screening, 2021Thymoquinone (TQ), the bioactive constituent of Nigella Sativa seeds, is a well-known natural compound for the management of several types of cancers. The anti-cancer properties of thymoquinone are thought to be operated via intervening with various oncogenic pathways, prevention of inflammation and oxidative stress, inhibition of angiogenesis and ...
Fatma, Alhmied +4 more
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In vitro toxicological properties of thymoquinone
Food and Chemical Toxicology, 2009Nigella sativa has been traditionally used for the treatment of inflammations, liver disorders, and arthritis. Experimentally, it has been demonstrated that N. sativa extracts and the main constituent of their volatile oil, thymoquinone, possess antioxidant, anti-inflammatory and hepato-protective properties.
M, Khader, N, Bresgen, P M, Eckl
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Therapeutic implications and clinical manifestations of thymoquinone
Phytochemistry, 2022Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and anti-inflammatory properties, validated in various disease models. The anti-cancer potential of TQ is goverened by anti-proliferation, cell cycle arrest, apoptosis induction ...
Manzar, Alam +5 more
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Effectiveness of thymoquinone in the treatment of experimental asthma.
La Clinica terapeutica, 2013PubMed ID ...
Omeroglu, G. +8 more
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