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Immunomodulatory and Anti-inflammatory Effects of Thymoquinone
Cardiovascular & Hematological Disorders-Drug Targets, 2018The immunomodulatory properties of Nigella sativa seed, as a basis of its clinical applications by many cultures have been reviewed. Thymoquinone (TQ) is one of the major bioactive components of the volatile oil of N. sativa seeds.The review on immunomodulatory and anti- inflammatory effects of TQ was focused on published literature in the English ...
Hanieh, Shaterzadeh-Yazdi +4 more
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Thymoquinone: Chemistry and Functionality
2020Thymoquinone (TQ) is found in nature as one of the constituents of the volatile oil fraction of black seeds (Nigella sativa L.). Nowadays, more research interest is directed toward TQ due to its versatile biological activities especially its anticancer potentials.
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Immunomodulatory effect of thymoquinone on atopic dermatitis
Molecular Immunology, 2018Atopic dermatitis (AD) or atopic eczema is a skin disease characterized with itching, increased serum level of immunoglobulin E, and peripheral eosinophilia. Thymoquinone (TQ) is an important ingredient of Nigella sativa seeds having antioxidant and anti-inflammatory effects.Present study investigates the immunomodulatory effects of Thymoquinone (TQ ...
Hina Aslam +3 more
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Thymoquinone Is a Potent Superoxide Anion Scavenger
Drug and Chemical Toxicology, 2003The antioxidant and pro-oxidant effects of thymoquinone (TQ), a natural main constituent of the volatile oil of Nigella saliva seeds, and a synthetic structurally-related tert-butylhydroquinone (TBHQ), were examined in vitro. Both TQ and TBHQ efficiently inhibited iron-dependent microsomal lipid peroxidation in a concentration-dependent manner with ...
Badary, Osama A. +3 more
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Nonenzymatic reduction of thymoquinone in physiological conditions
Free Radical Research, 2007Thymoquinone (TQ) is the bioactive constituent of the volatile oil of Nigella sativa L. and has been shown to exert antioxidant antineoplastic and anti-inflammatory effects. During the study of its possible mechanism of action, we found that TQ reacts chemically (i.e. nonenzymatically) with glutathione (GSH), NADH and NADPH.
K H, Khalife, G, Lupidi
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Anticancer Action of Thymoquinone
2018Thymoquinone (TQ) is a biologically active compound found in the Nigella sativa and extensively studied over the decades for its implications in diseases management without promoting the adverse side effects. An extensive number of researches have been performed to evaluate the efficacy of TQ in killing of cancer cells through modulating several ...
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Antimicrobial Action of Thymoquinone
2018In recent years, pathogens have adopted various mechanisms to combat the onslaught of currently available antibiotics. This led to the emergence of the phenomenon of antibiotic resistance in microorganisms. Antibiotic resistance has rendered many previously effective antibiotics into useless chemicals that are resulting in the dearth of available ...
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Hepatoprotective Action of Thymoquinone
2018Nigella sativa (black cumin) seeds and its principal bioactive component, thymoquinone (TQ), have been used for centuries in folk medicine because of their exceptional healing power to a wide range of diseases. Nigella sativa plant has been regarded as nature’s miracle herb.
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