Results 91 to 100 of about 313,790 (256)

Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance

open access: yesCell Reports
Summary: Medullary thymic epithelial cells (mTECs) are essential for the establishment of self-tolerance in T cells. Promiscuous gene expression by a subpopulation of mTECs regulated by the nuclear protein Aire contributes to the display of self-genomic ...
Aya Ushio   +7 more
doaj  

The Thymus in the Marsupials. [PDF]

open access: yesJournal of the Linnean Society of London, Zoology, 1898
n ...
openaire   +3 more sources

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]

open access: yes, 1996
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C.   +6 more
core  

Social disruption stress exacerbates alpha-galactosylceramide-induced hepatitis in mice [PDF]

open access: yes, 2005
Objective: Psychosocial stress has been suggested as a possible aggravating factor in liver diseases, however, the underlying mechanism has yet to be clarified.
Chida, Y, Kubo, C, Sonoda, J, Sudo, N
core  

Fingerprint Study of Thymus spp. by TLC

open access: yesJournal of Medicinal Plants, 2009
Background: Thymus is a widely used medicinal plant in food and pharmaceutical industries. Among different species of Thymus, T. vulgaris is used more than other species in therapeutic dosage forms.
H Hajimehdipoor   +6 more
doaj  

Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. [PDF]

open access: yes, 1987
The transmission of a lymphomagenic agent(s) from the bone marrow of irradiated mice to thymic target cells has been demonstrated by: (a) the induction of T cell lymphomas in nonirradiated thymic grafts implanted in irradiated, Thy-l-congenic mice, (b ...
Hansteen, GA   +5 more
core  

The thymus road to a T cell: migration, selection, and atrophy

open access: yesFrontiers in Immunology
The thymus plays a pivotal role in generating a highly-diverse repertoire of T lymphocytes while preventing autoimmunity. Thymus seeding progenitors (TSPs) are a heterogeneous group of multipotent progenitors that migrate to the thymus via CCR7 and CCR9 ...
Mario Ruiz Pérez   +6 more
doaj   +1 more source

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