Results 41 to 50 of about 7,297 (209)
The thyroid, the eyes and the gut: a possible connection [PDF]
Graves’ disease (GD) is an autoimmune disorder responsible for 60–90% of thyrotoxicosis, with an incidence of 1 to 2 cases per 1000 population per year in England.
Covelli, D., Ludgate, Marian Elizabeth
core +2 more sources
Glycosaminoglycans in Thyroid-Associated Ophthalmopathy
Glycosaminoglycan (GAG) accumulation in the retrobulbar space of patients with thyroid-associated ophthalmopathy (TAO) has been documented in a number of immunohistochemical studies. In order to gain further insight into possible immunopathogenic mechanisms, the influence of humoral immunity on retrobulbar fibroblasts (RF) as GAG producing cells as ...
KAHALY, G +4 more
openaire +3 more sources
Association of polymorphism in genes encoding κB inhibitors (IκB) with susceptibility to and phenotype of Graves' disease: a case-control study [PDF]
Background Genes related to the nuclear factor-κB (NF-κB), a key transcription factor involved in regulation of immune responses, are interesting candidates for association studies in autoimmune disorders.
Alina Kurylowicz +4 more
core +2 more sources
Teprotumumab Treatment for Thyroid-Associated Ophthalmopathy [PDF]
<b><i>Background:</i></b> Thyroid-associated ophthalmopathy (TAO), an autoimmune process affecting the tissues surrounding the eye, most commonly develops in individuals with Graves’ disease. It is disfiguring, can cause vision loss, and dramatically lessens the quality of life in patients.
openaire +2 more sources
The article is to overview papers: Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. Management of neonates born to women with Graves’ disease: a cohort study.
Yuliya Aleksandrovna Manuylova +1 more
doaj +1 more source
Diagnostic accuracy of short-time inversion recovery sequence in Graves' ophthalmopathy before and after prednisone treatment [PDF]
Introduction: In Graves' Ophthalmopathy, it is important to distinguish active inflammatory phase, responsive to immunosuppressive treatment, from fibrotic unresponsive inactive one.
Belfiore, M. P. +8 more
core +1 more source
Application of Agents Against Interferon-Gamma-Dependent Chemokines in Immunotherapy [PDF]
The CXC chemokine receptor (CXCR) 3 and its chemokines (CXCL9, CXCL10, CXCL11) are involved in the pathogenesis of autoimmune disesases. Under the influence of interferon (IFN) γ, the IFNγ-inducible chemokines are secreted by lymphocytes, and by ...
Antonelli, Alessandro +4 more
core +1 more source
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu +12 more
wiley +1 more source
Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future. [PDF]
Thyroid-associated orbitopathy (TAO) is the most common autoimmune disease of the orbit. It occurs more often in patients presenting with hyperthyroidism, characteristic of Graves' disease, but may be associated with hypothyroidism or euthyroidism.
De Los Angeles Gracia, M. +4 more
core +3 more sources
ABSTRACT Background and Aims CMT1H is a rare, autosomal dominant, demyelinating subtype of CMT caused by variants in FBLN5. Symptomatic cranial nerve involvement has never been reported in patients with CMT1H. Case Report We report a 45‐year‐old woman with a history of long‐standing diplopia.
Georgios Koutsis +11 more
wiley +1 more source

