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Annual Review of Medicine, 1992
Generalized resistance to thyroid hormone (GRTH) encompasses a heterogeneous group of conditions characterized by reduced responses of target tissues to thyroid hormone due to defects at the site of hormone action. In the majority of patients, GRTH is inherited as a dominant trait associated with mutations in the hormone-binding domain of the thyroid ...
R E, Weiss, S, Refetoff
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Generalized resistance to thyroid hormone (GRTH) encompasses a heterogeneous group of conditions characterized by reduced responses of target tissues to thyroid hormone due to defects at the site of hormone action. In the majority of patients, GRTH is inherited as a dominant trait associated with mutations in the hormone-binding domain of the thyroid ...
R E, Weiss, S, Refetoff
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Thyroid Hormone and the Kidney
Nephron, 2008Thyroid hormones affect both renal morphology and function. They are required for kidney growth and development, and thyroid deficiency results in decreased renal plasma flow and glomerular filtration rate and in impaired urinary concentration and dilution.
A I, Katz +2 more
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Current Opinion in Endocrinology, Diabetes & Obesity, 2012
To review several of the most recent and most important clinical studies regarding the effects of thyroid treatments on weight change, associations between thyroid status and weight, and the effects of obesity and weight change on thyroid function.Weight decreases following treatment for hypothyroidism.
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To review several of the most recent and most important clinical studies regarding the effects of thyroid treatments on weight change, associations between thyroid status and weight, and the effects of obesity and weight change on thyroid function.Weight decreases following treatment for hypothyroidism.
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Thyroid Hormones As Neurotransmitters
Thyroid, 1996During brain development, before the apparatus of neurotransmission has been set into place, many neurotransmitters act as growth regulators. In adult brain, their role in neurotransmission comes to the fore but neuronal plasticity and other growth-related processes are their continuing responsibility.
M B, Dratman, J T, Gordon
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Reviews in Endocrine and Metabolic Disorders, 2000
The syndromes of resistance to thyroid hormone (RTH) are generally characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free T 3 and/or T 4 (Refetoff et al., 1993). It is associated with an inappropriately normal or raised serum TSH characteristic of impaired thyrotroph sensitivity.
R E, Weiss, S, Refetoff
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The syndromes of resistance to thyroid hormone (RTH) are generally characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free T 3 and/or T 4 (Refetoff et al., 1993). It is associated with an inappropriately normal or raised serum TSH characteristic of impaired thyrotroph sensitivity.
R E, Weiss, S, Refetoff
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Current Biology
Animals interact with their environment in a dynamic manner, with behavior shaped by a combination of internal state and external cues. Seasonal changes in food availability, for instance, alter food-seeking strategies, whereas progress through life stages drives changes in sexual behaviors and shifts in social hierarchies that can modulate dominance ...
Daniel R, Hochbaum, Bernardo L, Sabatini
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Animals interact with their environment in a dynamic manner, with behavior shaped by a combination of internal state and external cues. Seasonal changes in food availability, for instance, alter food-seeking strategies, whereas progress through life stages drives changes in sexual behaviors and shifts in social hierarchies that can modulate dominance ...
Daniel R, Hochbaum, Bernardo L, Sabatini
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1982
Publisher Summary This chapter discusses the formation of thyroid hormones. The metabolic pathway that allows the synthesis of thyroid hormones from inorganic iodide has been extensively documented at the physiological level, the investigations being greatly facilitated by the use of the iodine isotopes.
J, Nunez, J, Pommier
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Publisher Summary This chapter discusses the formation of thyroid hormones. The metabolic pathway that allows the synthesis of thyroid hormones from inorganic iodide has been extensively documented at the physiological level, the investigations being greatly facilitated by the use of the iodine isotopes.
J, Nunez, J, Pommier
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Thyroid hormone and atherosclerosis
Vascular Pharmacology, 2010It is generally accepted that the euthyroid state is preferred for the cardiovascular system because both hyperthyroidism and hypothyroidism cause or accelerate cardiovascular diseases. And hypothyroidism is known to be associated with atherosclerosis and ischemic heart diseases.
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Thyroid Hormones and the Brain
Frontiers in Neuroendocrinology, 2001Significant progress has been made over the past 2 decades toward understanding the molecular basis of thyroid hormone action. It is now widely accepted that thyroid hormones play predominantly a nuclear role and function by regulating the transcription of specific target genes.
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