Results 241 to 250 of about 1,914,121 (297)

Gold‐Modified Mesoporous Carbon Enables Serum Metabolic Fingerprinting for Papillary Thyroid Carcinoma Diagnosis

Small Methods, EarlyView.
A novel MCHS‑Au‑LA substrate is developed for carbon‑gold nanostructure‐initiator mass spectrometry (C‑Au‑NIMS), which acquires metabolic fingerprints of serum samples from papillary thyroid carcinoma (PTC), benign thyroid nodules (BTN), and healthy controls (HC).
Wanwan Yi, Yida Huang, Jiayou Feng, Xiaowen Zhang, Yuheng Zhu, Kun Qian, Chang Lei, Zhongwei Lv, Chengzhong Yu   +8 more
wiley   +1 more source

Identification of a novel splicing variant of thyroid hormone receptor interaction protein 13 (TRIP13) in female infertility characterized by oocyte maturation arrest. [PDF]

J Assist Reprod Genet
Chen J, Liu Y, Wu X, Zhang Y, Huang W, Han W, Chen G, Xu Q, Chen H, Wu Q, Wang J, Huang J.   +11 more
europepmc   +1 more source

Drug discovery targeting thyroid hormone receptor <i>β</i> (THR<i>β</i>) for the treatment of liver diseases and other medical indications. [PDF]

Acta Pharm Sin B
Wang K, Chen F, Wang J, Liu H.
europepmc   +1 more source

Nonylphenol and Cetyl Alcohol Polyethoxylates Disrupt Thyroid Hormone Receptor Signaling to Disrupt Metabolic Health.

Endocrinology
Bérubé R, Murray B, Kocarek TA, Gurdziel K, Kassotis CD.   +4 more
europepmc   +1 more source

Disruption of Thyroid Hormone Receptor Thrab Leads to Female Infertility in Zebrafish.

Endocrinology
Ai N, Han CR, Zhao H, Cheng SY, Ge W.
europepmc   +1 more source

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Nuclear receptors for thyroid hormone

Journal of Endocrinological Investigation, 1978
The concept that thyroxine (T4) or triiodothyronine (T3) might act by modification of nuclear RNA synthesis was advanced by Tata in the early 1960’s (Tata, Ernster, and Suranyi, 1962). He reported that T4 induced new RNA and protein synthesis, and indicated later that the earliest observable effect was on the function of nuclear magnesium-dependent ...
L J, DeGroot, S, Refetoff, J, Bernal, P A, Rue, A H, Coleoni   +4 more
openaire   +4 more sources

Thyroid hormone receptors and reproduction

Journal of Reproductive Immunology, 2011
Thyroid disorders have a great impact on fertility in both sexes. Hyperthyroidism and hypothyroidism cause changes in sex hormone-binding globulin (SHBG), prolactin, gonadotropin-releasing hormone, and sex steroid serum levels. In females, thyroid hormones may also have a direct effect on oocytes, because it is known that specific binding sites for ...
Ralf, Dittrich, Matthias W, Beckmann, Patricia G, Oppelt, Inge, Hoffmann, Laura, Lotz, Torsten, Kuwert, Andreas, Mueller   +6 more
openaire   +2 more sources

A structural role for hormone in the thyroid hormone receptor

Nature, 1995
The crystal structure of the rat alpha 1 thyroid hormone receptor ligand-binding domain bound with a thyroid hormone agonist reveals that ligand is completely buried within the domain as part of the hydrophobic core. In addition, the carboxy-terminal activation domain forms an amphipathic helix, with its hydrophobic face constituting part of the ...
R L, Wagner, J W, Apriletti, M E, McGrath, B L, West, J D, Baxter, R J, Fletterick   +5 more
openaire   +2 more sources