Results 21 to 30 of about 2,507,137 (250)

A two-day-old hyperthyroid neonate with thyroid hormone resistance born to a mother with well-controlled Graves’ disease: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Resistance to thyroid hormone is a syndrome caused by thyroid hormone receptor β mutations, which are usually inherited in an autosomal-dominant pattern.
Yatsuga Shuichi   +6 more
doaj   +1 more source

Thyroid Hormone Induces Oral Cancer Growth via the PD-L1-Dependent Signaling Pathway

open access: yesCells, 2022
Oral cancer is a fatal disease, and its incidence in Taiwan is increasing. Thyroid hormone as L-thyroxine (T4) stimulates cancer cell proliferation via a receptor on integrin αvβ3 of plasma membranes.
Kuan-Wei Su   +12 more
doaj   +1 more source

Interaction of Human Chorionic Gonadotropin (hCG) and Asialo-hCG with Recombinant Human Thyrotropin Receptor. [PDF]

open access: yes, 1994
hCG is a putative thyroid stimulator. The present studies were undertaken to examine its interaction and that of its desialylated variant asialo-hCG with recombinant human TSH (hTSH) receptor (hTSHr). To this end, we transfected a human thyroid carcinoma
Mann, K.   +4 more
core   +1 more source

Cooperative Subtype Switch of Thyroid Hormone Receptor and Nuclear Receptor Corepressor Related Epithelial–Mesenchymal Transition in Papillary Thyroid Cancer [PDF]

open access: yes, 2021
Background and Objectives: Although thyroid hormones affect human cancer progression, the regulatory mechanism of thyroid hormone receptors in carcinogenesis has not been elucidated.
이잔디   +4 more
core   +1 more source

High concentration of estradiol has a negative correlation with free thyroxine during the second trimester of pregnancy

open access: yesEndocrine Connections, 2022
Objective: To explore the relationship between estradiol (E2) and thyroid function during the second trimester of pregnancy and the effect of E2 on sodium iodide transporter (NIS) expression in cultured thyroid cells. Materials and methods: We analyzed
Leqi He   +9 more
doaj   +1 more source

Thyroid-like function in the urochordate Ciona intestinalis [PDF]

open access: yes, 2011
In the studies reported in the manuscript I investigated the involvement of Iodine and thyroxine (Thyroid Hormone, T4) in Ciona intestinalis metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown.
Staiano, Leopoldo
core   +1 more source

Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland

open access: yesCommunications Biology, 2023
Thyroid hormone (3,5,3’-triiodothyronine, T3) is a key regulator of pituitary gland function. The response to T3 is thought to hinge crucially on interactions of nuclear T3 receptors with enhancers but these sites in pituitary chromatin remain ...
Young-Wook Cho   +10 more
doaj   +1 more source

Coexistence of resistance to thyroid hormone and ectopic thyroid: ten-year follow-up

open access: yesArchives of Endocrinology and Metabolism, 2016
SUMMARY Resistance to thyroid hormone (RTH) coexisting with ectopic thyroid is rare. Here we report a case of RTH with ectopic thyroid. A ten-year-old girl had been misdiagnosed as congenital hypothyroidism and treated with levothyroxine since she was ...
Man-Li Guo   +5 more
doaj   +1 more source

Activation of the RhoB signaling pathway by thyroid hormone receptor β in thyroid cancer cells. [PDF]

open access: yesPLoS ONE, 2014
Thyroid hormone receptor (TR) mediates the crucial effects of the thyroid hormone (T3) on cellular growth, development, and differentiation. Decreased expression or inactivating somatic mutations of TRs have been found in human cancers of the liver ...
Sayaka Ichijo   +7 more
doaj   +1 more source

Mechanism of thyroid hormone and its structurally similar contaminant bisphenol S exposure on retinoid metabolism in zebrafish larval eyes

open access: yesEnvironment International, 2023
The photoreceptor necessitates the retinoids metabolism processes in visual cycle pathway to regenerate visual pigments and sustain vision. Bisphenol S (BPS), with similar structure of thyroid hormone (TH), was reported to impair the light-sensing ...
Liguo Qiu   +5 more
doaj   +1 more source

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