Results 21 to 30 of about 948 (200)
, 2023 Nonalcoholic steatohepatitis (NASH) is a progressive stage of nonalcoholic fatty liver disease (NAFLD) and is characterized by steatosis, inflammation, hepatocyte ballooning, and fibrosis.
Yi Zhang (9093) +9 more
core +2 more sources
Thyroid Hormone Induces Oral Cancer Growth via the PD-L1-Dependent Signaling Pathway
Cells, 2022 Oral cancer is a fatal disease, and its incidence in Taiwan is increasing. Thyroid hormone as L-thyroxine (T4) stimulates cancer cell proliferation via a receptor on integrin αvβ3 of plasma membranes.
Kuan-Wei Su +12 more
doaj +1 more source
, 2016 An Inhibitor of the Interaction of Thyroid Hormone Receptor β and Glucocorticoid Interacting Protein
R. Kiplin Guy (160393) +1 more
core +2 more sources
Endocrine Connections, 2022 Objective: To explore the relationship between estradiol (E2) and thyroid function during the second trimester of pregnancy and the effect of E2 on sodium iodide transporter (NIS) expression in cultured thyroid cells. Materials and methods: We analyzed
Leqi He +9 more
doaj +1 more source
Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland
Communications Biology, 2023 Thyroid hormone (3,5,3’-triiodothyronine, T3) is a key regulator of pituitary gland function. The response to T3 is thought to hinge crucially on interactions of nuclear T3 receptors with enhancers but these sites in pituitary chromatin remain ...
Young-Wook Cho +10 more
doaj +1 more source
Coexistence of resistance to thyroid hormone and ectopic thyroid: ten-year follow-up
Archives of Endocrinology and Metabolism, 2016 SUMMARY Resistance to thyroid hormone (RTH) coexisting with ectopic thyroid is rare. Here we report a case of RTH with ectopic thyroid. A ten-year-old girl had been misdiagnosed as congenital hypothyroidism and treated with levothyroxine since she was ...
Man-Li Guo +5 more
doaj +1 more source
, 2015 The syndrome of resistance to thyroid hormone (RTH β) is an inherited disorder characterized by variable tissue hyposensitivity to 3,5,30-l-triiodothyronine (T3), with persistent elevation of free-circulating T3 (FT3) and free thyroxine (FT4) levels in ...
Esquiaveto-aun A.M. +6 more
core +2 more sources
Activation of the RhoB signaling pathway by thyroid hormone receptor β in thyroid cancer cells. [PDF]
PLoS ONE, 2014 Thyroid hormone receptor (TR) mediates the crucial effects of the thyroid hormone (T3) on cellular growth, development, and differentiation. Decreased expression or inactivating somatic mutations of TRs have been found in human cancers of the liver ...
Sayaka Ichijo +7 more
doaj +1 more source
Environment International, 2023 The photoreceptor necessitates the retinoids metabolism processes in visual cycle pathway to regenerate visual pigments and sustain vision. Bisphenol S (BPS), with similar structure of thyroid hormone (TH), was reported to impair the light-sensing ...
Liguo Qiu +5 more
doaj +1 more source
Molecular dynamics approach to the I431V mutational impact on thyroid hormone receptor-beta
Bibechana, 2018 The point mutations like I431V on thyroid hormone receptor-beta (THR-β) gene cause resistance to thyroid hormones (RTH) with the clinical diagnosis of elevated free triiodothyronine (T3) and free thyroxin (T4) but not suppressed thyroid stimulating ...
Tika Ram Lamichhane +3 more
doaj +3 more sources