Results 31 to 40 of about 2,758,127 (153)

Methods to assess iron and iodine status [PDF]

, 2008
Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin.
Zimmermann, Michael B., Zimmermann, M.B., Zimmermann MB   +2 more
core   +1 more source

Cooperative Subtype Switch of Thyroid Hormone Receptor and Nuclear Receptor Corepressor Related Epithelial–Mesenchymal Transition in Papillary Thyroid Cancer [PDF]

, 2021
Background and Objectives: Although thyroid hormones affect human cancer progression, the regulatory mechanism of thyroid hormone receptors in carcinogenesis has not been elucidated.
이잔디, 김인규, 조영석, 박선미, 이기쁨, Hyunji Kim, Jandee Lee, Seul Gi Lee, Young Suk Jo, In-Kyu Kim, Seonhyang Jeong, Sunmi Park, Gibbeum Lee   +12 more
core   +1 more source

Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands

, 2008
Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay.
Soni, Krunal, Raval, Preeti, Joharapurkar, A., Bandyopadhyay, Debdutta, Yevale, Digambar, Raval, S., Soni, K., Gandhi, Neha, Raval, P., Jain, Mukul R., Modi, H., Modi, Honey, Yevale, D., Bandyopadhyay, D., Jain, M., Jogiya, Digvijay, Raval, Saurin, Joharapurkar, Amit, Patel, P., Jogiya, D., Patel, Pankaj R.   +20 more
core   +1 more source

Molecular dynamics approach to the I431V mutational impact on thyroid hormone receptor-beta

Bibechana, 2018
The point mutations like I431V on thyroid hormone receptor-beta (THR-β) gene cause resistance to thyroid hormones (RTH) with the clinical diagnosis of elevated free triiodothyronine (T3) and free thyroxin (T4) but not suppressed thyroid stimulating ...
Tika Ram Lamichhane, Sharma Paudel, Binod Kumar Yadav, Hari Prasad Lamichhane   +3 more
doaj   +3 more sources

Mechanism of thyroid hormone and its structurally similar contaminant bisphenol S exposure on retinoid metabolism in zebrafish larval eyes

Environment International, 2023
The photoreceptor necessitates the retinoids metabolism processes in visual cycle pathway to regenerate visual pigments and sustain vision. Bisphenol S (BPS), with similar structure of thyroid hormone (TH), was reported to impair the light-sensing ...
Liguo Qiu, Shuhui Wei, Yunsheng Wang, Rui Zhang, Shaoguo Ru, Xiaona Zhang   +5 more
doaj   +1 more source

T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation

Molecular Metabolism, 2022
Objectives: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes important ...
Liora S. Katz, Carmen Argmann, Luca Lambertini, Donald K. Scott   +3 more
doaj   +1 more source

A Novel Role for Thyroid Hormone Receptor Beta in Cellular Radiosensitivity [PDF]

, 2008
Thyroid hormone receptors (THRs) widely govern cell growth, differentiation and metabolism acting in a ligand- and cofactor-dependent manner to modulate tissue-specific gene expression. Given a large variety of genes regulated by THRs and multiplicity of
Hiroyuki NAMBA, Namba, Hiroyuki, Saenko, Vladimir, Yamashita, Shunichi, Akulevich, Natallia, Yuka NAKAZAWA, Vladimir SAENKO, Sedliarou, Ilya, Michiko MATSUSE, Rogounovitch, Tatiana, Mitsytake, Norisato, Natallia AKULEVICH, Shunichi YAMASHITA, Tatiana ROGOUNOVITCH, Nakazawa, Yuka, Matsuse, Michiko, Norisato MITSUTAKE, Ilya SEDLIAROU   +17 more
core   +1 more source

Effects of Antihypertensive Drugs on Thyroid Function in Type 2 Diabetes Patients With Euthyroidism

Frontiers in Pharmacology, 2022
Objective: There is little literature about whether antihypertensive drugs would affect thyroid function in patients with euthyroid type 2 diabetes, which was significant in maintaining a proper balance of thyroid function.
Lijuan Yang, Xiuqin Sun, Yi Zhao, Hong Tao   +3 more
doaj   +1 more source

TSHR (thyroid stimulating hormone receptor). [PDF]

, 2009
TSHR (Thyroid Stimulating Hormone Receptor) gene DNA: position, structure, transcription Protein: structure, expression, localization, function Mutations: somatic and germinal mutations Disease/oncogenesis: Thyroid adenoma, Toxic multinodular goiter (
IOSCO, CARMELA, RHODEN, KERRY JANE
core   +2 more sources

Resistance to thyroid hormone in the absence of mutations in the thyroid hormone receptor genes

, 2000
Most people with resistance to thyroid hormone have mutant thyroid hormone receptors that interfere with the function of the normal receptor and produce a dominant mode of inheritance.
Refetoff, Samuel, Sadow, Peter, Reutrakul, Sirimon, Weiss, Roy   +3 more
core   +1 more source