Results 21 to 30 of about 26,033 (150)
Frontiers in Endocrinology, 2014 Cerebellum development is sensitive to thyroid hormone (TH) levels, as THs regulate neuronal migration, differentiation and myelination. Most effects of THs are mediated by the TH receptor (TR) isoforms TRb1, TRb2 and TRa1.
Larissa Costa Faustino +1 more
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The Mutant Thyroid Hormone Receptor Beta R320P Causes Syndrome of Resistance to Thyroid Hormone
Case Reports in Endocrinology, 2018 A 31-year-old Japanese male patient with a history of atrial fibrillation showed elevated serum levels of free thyroxine and triiodothyronine and a normal level of thyrotropin. The same abnormal hormone pattern was also found in his son. These data indicated that the index patient and the son have thyroid hormone resistance syndrome.
Tetsuya Kimura +3 more
openaire +3 more sources
Frontiers in Endocrinology, 2019 Direct development is a reproductive mode in amphibians that has evolved independently from the ancestral biphasic life history in at least a dozen anuran lineages.
Mara Laslo +2 more
doaj +1 more source
The Korean Journal of Internal Medicine, 2008 Resistance to thyroid hormone (RTH) is a syndrome characterized by reduced sensitivity to the thyroid hormone. It is generally caused by mutations in the thyroid hormone receptor beta (TR beta) gene. On the basis of its clinical features, two different forms of this syndrome have been described: generalized resistance and pituitary resistance.
Kim, Ji Yon +6 more
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Thyroid Hormone Receptor Beta Gene Mutation (P453A) in a Family Producing Resistance to Thyroid Hormone [PDF]
Experimental and Clinical Endocrinology & Diabetes, 2008 Resistance to thyroid hormone (RTH) is a dominantly inherited syndrome characterized by decreased responsiveness of target tissues to thyroid hormone. Two members of a Turkish family, a mother and son, had thyroid function tests suggestive of resistance to thyroid hormone (RTH).The clinical presentation was, however, different.
T, Bayraktaroglu +5 more
openaire +2 more sources
Thyroid Hormone Resistance in the Heart: Role of the Thyroid Hormone Receptor β Isoform [PDF]
Endocrinology, 2004 Several cardiac genes possess thyroid hormone (TH) response elements regulated by TH receptors. Mutation in TR-beta gene causes the human syndrome of resistance to TH, which is characterized by elevated serum concentration of T(4) and T(3) and variable degrees of insensitivity to TH.
Tania M, Ortiga-Carvalho +6 more
openaire +2 more sources
G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish. [PDF]
PLoS Genetics, 2017 Estrogens act by binding to estrogen receptors alpha and beta (ERα, ERβ), ligand-dependent transcription factors that play crucial roles in sex differentiation, tumor growth and cardiovascular physiology.
Shannon N Romano +5 more
doaj +1 more source
Peroxisome Proliferator-Activated Receptors and Shock State
The Scientific World Journal, 2006 Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are related to retinoid, steroid, and thyroid hormone receptors.
Emanuela Esposito +2 more
doaj +1 more source
Cell Reports, 2017 The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms that regulate appetite and body weight will provide the rationale for the design of anti-obesity therapies.
Saira Hameed +17 more
doaj +1 more source
Environment International, 2021 This study investigated concentrations of phthalates (diesters of phthalic acids) in blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus), bowhead whales (Balaena mysticetus) and polar bears (Ursus maritimus ...
Heli Routti +7 more
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