Results 41 to 50 of about 26,033 (150)

Pituitary resistance to thyroid hormone caused by a novel mutation (H435A) in the thyroid hormone receptor beta [PDF]

Medicine, 2018
In patients with pituitary thyroid hormone resistance, the ability of the pituitary gland to detect (and down-regulate) the increase of triiodothyronine is selectively impaired, while the periphery remains sensitive to triiodothyronine levels, producing symptoms of peripheral thyrotoxicity.
Yu, Changzhen, Zhao, Junyu, Yao, Jinming, Wang, Huanjun, Shang, Hongxia, Zhang, Rui, Cui, Yujiao, Wang, Likang, Dong, Jianjun, Liao, Lin   +9 more
openaire   +2 more sources

Molecular characterization of thyroid hormone receptor beta from Schistosoma japonicum and assessment of its potential as a vaccine candidate antigen against schistosomiasis in BALB/c mice

Parasites & Vectors, 2012
Background Thyroid hormones (TH) modulate growth, development and differentiation and metabolic processes by interacting with thyroid hormone receptors (THRs).
Qiu Chunhui, Liu Shengfa, Hong Yang, Fu Zhiqiang, Wei Meimei, Ai Dezhou, Lin Jiaojiao   +6 more
doaj   +1 more source

Endocrinological aspects of dietary habits

Czech Journal of Food Sciences, 2004
Dietary habits reflect both the recent economic possibilities and the cultural history of individual human populations. They may influence endocrine systems and thus affect the health of the respective populations in several manners: (1) People consuming
O. Lapčík
doaj   +1 more source

Thyroid Hormones, Thyromimetics and Their Metabolites in the Treatment of Liver Disease

Frontiers in Endocrinology, 2018
The signaling pathways activated by thyroid hormone receptors (THR) are of fundamental importance for organogenesis, growth and differentiation, and significantly influence energy metabolism, lipid utilization and glucose homeostasis.
Marta A. Kowalik, Amedeo Columbano, Andrea Perra   +2 more
doaj   +1 more source

Morphology and physiology of the epiphyseal growth plate.

Folia Histochemica et Cytobiologica, 2009
The epiphyseal growth plate develops from the cartilaginous-orientated mesenchymal cells that express SOX family genes. This multilayer structure is formed by the proliferation and hypertrophy of cells that synthesize the extracellular matrix composed of
Robert Klepacz, Michał Solecki, Michał Szumiło, Anjalee Dave, Ankit Patel, Sagar Patel, Rabia Farooquee, Agnieszka Korobowicz, Justyna Szumiło, Franciszek Burdan, Jarosław Dudka   +10 more
doaj   +1 more source

The Role of Chest Radiograph, Procalcitonin and Moxifloxacin in Diagnosis and Management of Breast Cancer Patients with COVID-19

Acta Medica Indonesiana, 2020
Global widespread of current coronavirus disease 2019 (COVID-19) pandemic has emerged huge predicament to healthcare systems globally. This disease caused by a new beta-type coronavirus, known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
Ikhwan Rinaldi, Abdul Muthalib, Pujo Astowo, Bambang Irawan, Nelly Susanto, Lingga Magdalena, Ilham H.R. Tulus Maha, Satrio Wicaksono   +7 more
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Epigenetic Regulation of Thyroid Hormone Receptor Beta in Renal Cancer

PLoS ONE, 2014
Thyroid hormone receptor beta (THRB) gene is commonly deregulated in cancers and, as strengthened by animal models, postulated to play a tumor-suppressive role. Our previous studies revealed downregulation of THRB in clear cell renal cell carcinoma (ccRCC), but the culpable mechanisms have not been fully elucidated.
Anna Wojcicka, Agnieszka Piekielko–Witkowska, Hanna Kedzierska, Beata Rybicka, Piotr Poplawski, Joanna Boguslawska, Adam Master, Alicja Nauma   +7 more
openaire   +4 more sources

The Case for TAAR1 as a Modulator of Central Nervous System Function

Frontiers in Pharmacology, 2018
TAAR1 is widely expressed across the mammalian brain, particularly in limbic and monoaminergic areas, allegedly involved in mood, attention, memory, fear, and addiction.
Grazia Rutigliano, Grazia Rutigliano, Alice Accorroni, Alice Accorroni, Riccardo Zucchi   +4 more
doaj   +1 more source

Nuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells

Molecules, 2019
We recently established a KAIMRC1 cell line that has unique features compared to the known breast cancer cell lines, MCF7 and MDA-MB231. To characterize it further, we investigated the expression profile of nuclear receptors and their respective co ...
Atef Nehdi, Rizwan Ali, Alshaimaa Alhallaj, Hajar Alzahrani, Nosaibah Samman, Abdullah Mashhour, Omar Baz, Tlili Barhoumi, Bandar Alghanem, Abdullatif Khan, Lolwah Alriyees, Mohamed Boudjelal   +11 more
doaj   +1 more source

A Novel Role for Thyroid Hormone Receptor Beta in Cellular Radiosensitivity

Journal of Radiation Research, 2008
Thyroid hormone receptors (THRs) widely govern cell growth, differentiation and metabolism acting in a ligand- and cofactor-dependent manner to modulate tissue-specific gene expression. Given a large variety of genes regulated by THRs and multiplicity of cellular processes potentially influenced by THRs, we addressed the role of THRB (thyroid hormone ...
Michiko, Matsuse, Vladimir, Saenko, Ilya, Sedliarou, Tatiana, Rogounovitch, Yuka, Nakazawa, Norisato, Mitsutake, Natallia, Akulevich, Hiroyuki, Namba, Shunichi, Yamashita   +8 more
openaire   +2 more sources