Results 121 to 130 of about 2,990,232 (287)

Resistance to thyroid hormone in a Chinese family with R429Q mutation in the thyroid hormone receptor beta gene

, 2005
The combination of elevated serum levels of free thyroid hormones with non-suppressed thyroid-stimulating hormone suggests the differential diagnoses of resistance to thyroid hormone or thyroid-stimulating hormone-secreting pituitary tumour.
Yiu, SF, Lam, CW, Chan, AOK, Kong, APS, Tiu, SC   +4 more
core  

Nutritional management, dietary intervention, and long‐term monitoring in pediatric Prader–Willi syndrome: A 3‐year case‐based clinical observation

Nutrition in Clinical Practice, EarlyView.
Abstract Nutritional management is fundamental in Prader–Willi syndrome (PWS), but longitudinal data from routine pediatric practice are limited. We describe a 3‐year nutritional follow‐up of a boy with PWS complicated by obesity, insulin resistance, dyslipidemia, hyperuricemia, and fatty liver.
Peipei Chen, Hui Pan, Wei Chen
wiley   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

Association between sensitivity to thyroid hormones and trabecular bone score in euthyroid individuals: a population-based cross-sectional study

BMC Musculoskeletal Disorders
Background Thyroid hormone is a known pivotal factor that affects bone metabolism; however, whether bone microarchitecture is associated with thyroid hormone sensitivity is poorly understood.
Zihan Chen, Yuxiong Chen, Yuanmeng Li, Zhiwei Leng, Naishi Li, Weibo Xia   +5 more
doaj   +1 more source

The relationship between thyroid hormones sensitivity and hyperhomocysteinemia: a cross-sectional study based on Chinese health check-up population

Frontiers in Endocrinology
BackgroundIt is unclear if impaired thyroid hormone sensitivity interacts with homocysteine (Hcy), a known risk factor for cardiovascular diseases (CVD), despite the fact that it has been identified as a prevalent metabolic condition.We aimed to analyze ...
Rui Gong, Jiao Xie, Lixia Yu, Yan Ling, Shi Wang, Rui Min, Sanping Xu   +6 more
doaj   +1 more source

Thyroid hormone resistance resulting from a novel mutation in the THRB gene in a Chinese child: A case report. [PDF]

Medicine (Baltimore), 2023
Feng J, Lin S, Wang W, Chen Q, Wang W, Li J, Wang X.   +6 more
europepmc   +1 more source

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

Polymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

The clinical characteristics and gene mutations associated with thyroid hormone resistance syndrome coexisting with pituitary tumors. [PDF]

Front Endocrinol (Lausanne), 2023
Zhao J, Xu L, Li C, Wang F, Liao L, Dong J.   +5 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

The correlation between impaired thyroid hormone sensitivity and 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with type 2 diabetes mellitus

Diabetes & Vascular Disease Research
Background Atherosclerotic cardiovascular disease (ASCVD) is one of the common complications in patients with type 2 diabetes mellitus (T2DM). Thyroid hormones affect cardiovascular function through multiple pathways. Purpose To explore the relationships
Yuqian Zhang, Juan Wang, Huaner Wang, Yefan Yang, Junni Zhu, Lihua Ma, Jingfang Liu   +6 more
doaj   +1 more source