Results 161 to 170 of about 2,990,232 (287)

Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia. Abstract The presence of a small optic disc on funduscopy is prerequisite for the diagnosis of optic nerve hypoplasia (ONH). Visual acuity may be normal. However, amblyopia can occur in ONH. A relative afferent pupillary light defect indicates unilateral or asymmetrical ONH.
Michael S. Salman
wiley   +1 more source

Multisystem developmental abnormalities and insulin resistance in ADTKD‐HNF1B with the p.E105K variant: A clinical conundrum

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang   +5 more
wiley   +1 more source

DiaActive protocol: A randomized controlled trial of cognitive‐motor multicomponent exercise to reduce fall rate in older adults with diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction Older adults with diabetes have an increased risk of falls due to neuropathy, impaired bone health and cardiovascular disease, resulting in significant morbidity and mortality. Conventional fall‐prevention programmes primarily target strength and balance, while cognitive‐motor integration, essential for safe mobility in complex ...
Aksayan Arunanthy Mahalingasivam   +4 more
wiley   +1 more source

Incorporation of Carob Into a High‐Fat Meal Influences Subjective Satiety, Ghrelin and PYY Regulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Dietary components that influence appetite‐related hormones and subjective satiety may help regulate food intake. Aqueous carob (Ceratonia siliqua L.) preparations may have a role in postprandial appetite regulation. Aims To investigate the effects of an aqueous carob preparation incorporated into a high‐fat meal on postprandial ...
Charalampia Amerikanou   +5 more
wiley   +1 more source

Levodopa induces thyroid function regulation in a patient with thyroid hormone resistance and Parkinson's disease: a case report. [PDF]

open access: yesFront Endocrinol (Lausanne)
Rozo-Paz G   +4 more
europepmc   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

open access: yesThe FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe   +5 more
wiley   +1 more source

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