Results 201 to 210 of about 2,990,232 (287)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Antiresorptive therapy influence on peri‐implant diseases: Clinical implications and osteoimmunological perspectives

Periodontology 2000, EarlyView.
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata, Frank Schwarz, Reinhard Gruber   +2 more
wiley   +1 more source

Thyroid Hormone Resistance: A 17-Year Follow-up Case Report.

Endocr Metab Immune Disord Drug Targets
Giusto C, Passeri M, Sperti P, Nardone I, Wolde Sellasie S, Zaccaria S, Longo L, Lo Deserto P, Amendola S, Uccioli L.   +9 more
europepmc   +1 more source

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

Identification of a novel mutation in the thyroid hormone receptor β gene that causes thyroid hormone resistance syndrome: A case report. [PDF]

Mol Med Rep, 2019
Wang J, Lv H.
europepmc   +1 more source

Exercise and physiological monitoring in isolated, confined and extreme environments and space analogues: A scoping review

Experimental Physiology, EarlyView.
Abstract This scoping review synthesized evidence on physical activity/exercise and physiological monitoring in isolated, confined and extreme (ICE) environments, with emphasis on Antarctic missions and space analogues. ICE exposures combine cold stress, confinement, disrupted light–dark cycles and psychosocial strain, which can challenge ...
Gustavo S. O. Lima, Kaline V. F. Dinis, Leonardo P. Silva, Nayanne B. Sousa, Maria Keiliane F. S. Silva, Danilo C. Talhari, Josélia S. Almeida, Michele M. Moraes, Rosa M. E. Arantes, Marcos A. Nascimento, Thiago T. Mendes   +10 more
wiley   +1 more source

Physical activity partly inhibits autonomic imbalance, immune dysfunction and quality of life induced by chronic shiftwork in policemen

Experimental Physiology, EarlyView.
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos, Jeanne S. Tavares‐Vasconcelos, Anamei Silva‐Reis, Maysa A. R. Brandão‐Rangel, Rayssa T. Morais‐Felix, Fernando A. Santa‐Rosa, André L. L. Bachi, Viviane Soares, Omid Salehian, Claudio R. Frison, Rodolfo P. Vieira, Regiane Albertini   +11 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source