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Resistance to Thyroid Hormones

Archives of Internal Medicine, 1982
• Five patients from two unrelated families were found to have goiter and elevated serum concentrations of thyroxine (T 4 ) and triiodothyronine (T 3 ) without symptoms or signs of hyperthyroidism. All had measurable concentrations of thyroid stimulating hormone (TSH), and in four who were tested, there was an increase in TSH concentration following ...
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Thyroid Hormone Resistance

1999
Thyroid hormones (thyroxine T4, triiodothyronine T3) regulate many cellular func-tions in virtually every type of tissue. The diverse responses to thyroid hormone include regulation of growth, the metabolic rate, muscular activity, and myocardial contractility.
V. Krishna K. Chatterjee   +2 more
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Thyroid Hormone Resistance

2011
Thyroid hormone resistance is defined as a dominant hereditary condition in which the gene for the thyroid hormone receptor protein has mutated so that the normal binding of thyroid hormone on the T3 receptors in the cell nuclei of different organs is reduced.
Ernst Nyström   +4 more
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Resistance to Thyroid Hormone

2003
Fuller Albright introduced the concept of hormone resistance in the 1940s (1,2). In the ensuing half century, multiple hormone-resistance syndromes were described, including resistance to thyroid hormone (RTH) by Refetoff, DeWind, and DeGroot in 1967 (3).
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[Resistance to thyroid hormone].

Nihon rinsho. Japanese journal of clinical medicine, 1994
Resistance to thyroid hormone (RTH), Refetoff's syndrome, is a syndrome of reduced responsiveness of target tissue to thyroid hormone (TH). Inheritance is usually autosomal dominant except in one family, being recessive. Since a point mutation was first discovered in the thyroid hormone receptor (TR) beta gene of a subject with RTH, approximately 93 ...
K, Takeda, K, Hashimoto
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Thyroid hormone resistance.

Annals of clinical research, 1981
General resistance to the action of thyroid hormones is characterized by increased levels of thyroid hormones and normal thyroid hormone binding proteins but clinical euthyroidism. There is a wide clinical spectrum ranging from patients with congenital goitre and signs of subclinical hypothyroidism to subjects with no physical abnormality.
B A, Lamberg, K, Liewendahl
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[Resistance to thyroid hormone].

Nihon rinsho. Japanese journal of clinical medicine, 2007
Resistance to thyroid hormone is a syndrome involving reduced responsiveness of target tissues to thyroid hormone. Most cases involve mutations of the thyroid hormone receptor beta gene. Since many patients demonstrate tachycardia, goiter and elevated serum thyroid hormone levels, some patients have been misdiagnosed with Graves' disease, and nearly ...
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Thyroid hormone resistance and pregnancy

BJOG: An International Journal of Obstetrics & Gynaecology, 2003
Simon, Kane, Robert, Fox, Colin, Close
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New Developments in the Diagnosis and Treatment of Thyroid Cancer

Ca-A Cancer Journal for Clinicians, 2013
David F Schneider, Herbert Chen
exaly  

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