Results 191 to 200 of about 42,240 (230)
Some of the next articles are maybe not open access.
Thyroide hormone resistance syndromes
Endocrinología y Nutrición (English Edition), 2011Thyroid hormone resistance syndromes are a group of genetic conditions characterized by decreased tissue sensitivity to thyroid hormones. Three syndromes, in which resistance to hormone action is respectively due to mutations in the gene encoding for thyroid hormone receptor TRβ, impaired T4 and T3 transport, and impaired conversion of T4 to T3 ...
openaire +2 more sources
Syndromes of thyroid hormone resistance
American Journal of Physiology-Endocrinology and Metabolism, 1982Resistance to the action of thyroid hormone can involve both peripheral tissues and the pituitary (global resistance), the pituitary only or peripheral tissues alone. Global resistance is of variable severity and has been observed in more than 60 individuals, the majority occurring in 17 families.
openaire +2 more sources
Syndromes of Resistance to Thyroid Hormone Action
2015Thyroid hormone (TH) action is crucial for the development of several tissues. A number of syndromes are associated with reduced responsiveness to thyroid hormones, expanding the original definition of thyroid hormone resistance, firstly described by Refetoff and collaborators in 1967, which is characterized by elevated circulating levels of T4 and T3 ...
L. Persani, I. Campi, F. Marelli
openaire +1 more source
Syndromes of Resistance to Thyroid Hormone Action
2019Thyroid hormone (TH) action is crucial for the development of several tissues.A number of syndromes are associated with reduced responsiveness to thyroid hormones, expanding the original definition of thyroid hormone resistance, firstly described by Refetoff and collaborators in 1967, which is characterized by elevated circulating levels of T4 and T3 ...
Luca, Persani, Irene, Campi
openaire +2 more sources
Syndromes of Resistance to Thyroid Hormone
2022Abstract Disorders of cellular uptake, metabolism, or action of thyroid hormones comprise syndromes of resistance to thyroid hormone. Reduced entry of thyroid hormones into the central nervous system via a membrane transporter mediates severe mental and psychomotor retardation associated with peripheral hyperthyroidism.
Carla Moran +2 more
openaire +1 more source
Molecular and Cellular Endocrinology, 2017
Thyroid hormone (TH) is crucial for normal development and metabolism of virtually all tissues. TH signaling is predominantly mediated through binding of the bioactive hormone 3,3',5-triiodothyronine (T3) to the nuclear T3-receptors (TRs). The intracellular TH levels are importantly regulated by transporter proteins that facilitate the transport of TH ...
Stefan Groeneweg +2 more
exaly +3 more sources
Thyroid hormone (TH) is crucial for normal development and metabolism of virtually all tissues. TH signaling is predominantly mediated through binding of the bioactive hormone 3,3',5-triiodothyronine (T3) to the nuclear T3-receptors (TRs). The intracellular TH levels are importantly regulated by transporter proteins that facilitate the transport of TH ...
Stefan Groeneweg +2 more
exaly +3 more sources
Journal of Clinical Endocrinology and Metabolism, 1980
We have previously described an inherited syndrome best explained as peripheral resistance to the action of thyroid hormone. So far, studies were carried out principally in two affected siblings, the third being too young. These studies concentrated on the demonstration of authenticity of the circulating thyroid hormones, their metabolism, the lack of ...
Samuel Refetoff +2 more
exaly +3 more sources
We have previously described an inherited syndrome best explained as peripheral resistance to the action of thyroid hormone. So far, studies were carried out principally in two affected siblings, the third being too young. These studies concentrated on the demonstration of authenticity of the circulating thyroid hormones, their metabolism, the lack of ...
Samuel Refetoff +2 more
exaly +3 more sources
[Syndromes of thyroid hormone resistance].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1997The authors have presented the contemporary knowledge concerning the syndromes of thyroid hormone resistance. There are three forms of this syndrome: Generalized Resistance of Thyroid Hormone, Pituitary Resistance to Thyroid Hormone and Peripheral Tissue Resistance to Thyroid Hormone. The illness appears in both family and sporadic forms. Etiology with
J M, Wis, M, Grzywa
openaire +1 more source
Biochimie, 1999
Lipoproteins, especially HDL, are carriers of a small fraction of the thyroid hormones in plasma and participate in the intracellular transport of T4. In previous work we showed that a brief period of hypothyroidism alters the hormone distribution among the lipoproteins, causing a decrease in VLDL and LDL binding despite a relative increase in VLDL and
BENVENGA, Salvatore, ROBBINS J.
openaire +2 more sources
Lipoproteins, especially HDL, are carriers of a small fraction of the thyroid hormones in plasma and participate in the intracellular transport of T4. In previous work we showed that a brief period of hypothyroidism alters the hormone distribution among the lipoproteins, causing a decrease in VLDL and LDL binding despite a relative increase in VLDL and
BENVENGA, Salvatore, ROBBINS J.
openaire +2 more sources
[Syndrome of resistance to thyroid hormones].
Presse medicale (Paris, France : 1983), 1994Although rare, thyroid hormone resistance syndrome should be suspected on a biological profile combining high thyroid hormone and non-suppressed TSH plasma levels. Resistance to thyroid hormone can be classified into 3 forms: generalized, pituitary and peripheral, all three showing tissue resistance heterogeneity from one person to another, and from ...
C, Mechain +4 more
openaire +1 more source