Results 51 to 60 of about 320 (154)

Effect of Aerobic Exercise on Thyroid Hormones and Quality of Life in Obese Postmenopausal Women

open access: yesMedical Laboratory Journal, 2018
Background and objectives: Studies have shown that exercise can affect hormone secretion and some metabolic and endocrine functions. The aim of this study was to assess the effect of eight weeks of aerobic training on thyroid hormones and quality of life
Mehrdad Fathi   +3 more
doaj  

Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors

open access: yesScientific Reports, 2018
Arginine-vasopressin (AVP) neurons exist in the hypothalamus, a major region of the diencephalon, and play an essential role in water balance. Here, we established the differentiation method for AVP-secreting neurons from human embryonic stem cells ...
Koichiro Ogawa   +15 more
doaj   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Thyrotropin-Releasing Hormone and Food Intake in Mammals: An Update

open access: yesMetabolites
Thyrotropin-releasing hormone (TRH; pGlu-His-Pro-NH2) is an intercellular signal produced mainly by neurons. Among the multiple pharmacological effects of TRH, that on food intake is not well understood.
Yamili Vargas   +5 more
doaj   +1 more source

Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents

open access: yesMolecules, 2009
Prodrug design for brain delivery of small- and medium-sized neuropeptides was reviewed, focusing on thyrotropin-releasing hormone and structurally related peptides as examples.
Laszlo Prokai, Katalin Prokai-Tatrai
doaj   +1 more source

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source

The Influence of Different Light Spectra on Broiler Chicken Endocrine Systems and Productivity

open access: yesAnimals
In birds, light can penetrate the cranial bones and reach deep brain regions, where non-visual photoreceptors, especially in the hypothalamus, detect spectral and photoperiodic cues.
Lenuța Galan   +2 more
doaj   +1 more source

Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone–Binding Globulin Expression

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Sex hormone–binding globulin (SHBG) is a sex hormone carrier. We aimed to characterize the role of pregnane X receptor (PXR), a major regulator of drug metabolism, in SHBG regulation. Serum SHBG was measured in four clinical trials (n = 61) and expression in in vitro experiments in human 3D hepatocyte spheroids and HepG2 cells.
Maria H. Ahonen   +5 more
wiley   +1 more source

Tanycytes and the Control of Thyrotropin-Releasing Hormone Flux Into Portal Capillaries

open access: yesFrontiers in Endocrinology, 2019
Central and peripheral mechanisms that modulate energy intake, partition and expenditure determine energy homeostasis. Thyroid hormones (TH) regulate energy expenditure through the control of basal metabolic rate and thermogenesis; they also modulate ...
Adair Rodríguez-Rodríguez   +6 more
doaj   +1 more source

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