Results 1 to 10 of about 18,009 (296)
PLoS ONE, 2020 BackgroundIn real-world practice settings, there is insufficient evidence on the efficacy of antiplatelet drugs, including clopidogrel, aspirin, and ticlopidine, in stroke prevention.PurposeTo compare the efficacies between aspirin and clopidogrel and ...
Yi-Sin Wong +3 more
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Frontiers in Neurology, 2019 Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung +10 more
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Ticlopidine and Clopidogrel [PDF]
Circulation, 1999 Abstract —The thienopyridines ticlopidine and clopidogrel are inhibitors of platelet function in vivo. Their mode of action has not been defined, but it appears that they require conversion to as yet unidentified metabolites that are noncompetitive antagonists of the platelet ADP receptor. Inhibition
Martin J. Quinn, Desmond J. Fitzgerald
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Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Mediators of Inflammation, 2014 Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer.
Joanna Lecka +3 more
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Control of biofilm from single and multispecies bacteria associated with food spoilage using metabolite of Streptomyces sp. KP110 and Pseudomonas fluorescens JB 3B [PDF]
Scientific ReportsFood spoilage bacteria are responsible for food spoilage and often fabricate biofilms on various surfaces. Naturally, biofilms are constructed by multiple bacterial species. These biofilms are more difficult to control compared to single species biofilms.
Budhiarto Halim +2 more
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Ecotoxicology and Environmental Safety, 2023 Ticlopidine exerts its anti-platelet effects mainly by antagonizing platelet p2y12 receptors. Previously, a few studies have shown that ticlopidine can induce liver injury, but the exact mechanism of hepatotoxicity remains unclear.
Rong Xu +15 more
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Ecotoxicology and Environmental Safety, 2022 Ticlopidine has inhibitory effects on platelet aggregation via ADP (adenosine diphosphate), platelet release reaction and depolymerization. In clinical practice, it is commonly used to prevent heart, cerebrovascular and other thromboembolic diseases ...
Rong Xu +9 more
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Ticlopidine and aspirin interactions. [PDF]
Heart, 1997 The risk-benefit balance when aspirin is compared with aspirin combined with ticlopidine is being investigated in several multicentre trials (MUSIC and WEST II versus TASTE, MUST, and STARS respectively). Cardiologists follow one of two strategies. Some prefer a more aggressive antiplatelet regimen, disregarding the risk of neutropenia (0.7%) because ...
Luisa Gregorini, J. Marco
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Neuroborreliosis in patient with aplastic anaemia secondary to therapy with ticlopidine [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2010 Introduction. Aplastic anaemia is a rare but potentially fatal complication of treatment with ticlopidine. Case Outline. We present a 55-year-old male with aplastic anaemia which developed after 45 days of the therapy with 200 mg ticlopidine to ...
Čolović Milica +4 more
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Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review
Dermatologica Sinica, 2014 Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus.
Yi-Ching Chen, Yu-Hung Wu
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