PLoS ONE, 2020 BackgroundIn real-world practice settings, there is insufficient evidence on the efficacy of antiplatelet drugs, including clopidogrel, aspirin, and ticlopidine, in stroke prevention.PurposeTo compare the efficacies between aspirin and clopidogrel and ...
Yi-Sin Wong +3 more
doaj +2 more sources
Frontiers in Neurology, 2019 Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung +10 more
doaj +2 more sources
Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Mediators of Inflammation, 2014 Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer.
Joanna Lecka +3 more
doaj +2 more sources
Double-Blind Study of the Safety of Clopidogrel With and Without a Loading Dose in Combination With Aspirin Compared With Ticlopidine in Combination With Aspirin After Coronary Stenting [PDF]
Circulation, 2000 BACKGROUND Combination therapy with the ADP receptor antagonist ticlopidine plus aspirin has emerged as standard care after coronary stenting. Clopidogrel, a new ADP receptor antagonist, has greater molar potency than ticlopidine and better safety ...
Michel E. Bertrand +4 more
openalex +2 more sources
Multivariate Adjustments for Average Equivalence Testing. [PDF]
Stat MedABSTRACT Multivariate (average) equivalence testing is widely used to assess whether the means of two conditions of interest are “equivalent” for different outcomes simultaneously. In pharmacological research for example, many regulatory agencies require the generic product and its brand‐name counterpart to have equivalent means both for the AUC and ...
Boulaguiem Y +4 more
europepmc +2 more sources
Integrated Genomic and GEO Data Analysis Reveals Therapeutic Targets for Rosacea. [PDF]
J Cosmet DermatolABSTRACT Background Rosacea is a chronic inflammatory facial disorder with limited therapeutic options, severely impacting patients' quality of life. The identification of druggable genes plays a crucial role in facilitating the development of effective therapeutic strategies.
Deng X, He S, Long H, Xiao J, Xie Z.
europepmc +2 more sources
A Thrombocytopenic Thrombotic Purpura in a Patient With a Metastatic HER2+ Breast Cancer: Description of a Case Report. [PDF]
Clin Case RepABSTRACT Paraneoplastic (p) TTP is a rare syndrome characterized by an immune‐induced, generalized microangiopathy associated with solid or hematological tumors. This case, reporting a patient with a metastatic HER2+ breast cancer and a pTTP, highlights the rarity of this entity, its difficult and challenging diagnosis, and the complexity of its ...
Longo R +9 more
europepmc +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review
Dermatologica Sinica, 2014 Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus.
Yi-Ching Chen, Yu-Hung Wu
doaj +1 more source
Stroke following percutaneous coronary intervention : type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12 [PDF]
, 2016 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015.
Berry, Colin +11 more
core +1 more source