Results 11 to 20 of about 18,009 (296)

THE EFFECTIVENESS OF CLOPIDOGREL AS AN ANTITHROMBOTIC COMPARED TO TICLOPIDINE AND ASPIRIN (META-ANALYSIS) [PDF]

Jurnal Farmasi Sains dan Komunitas, 2017
Clopidogrel, an antithrombotic drug, has been proven by FDA as Plavix® was initially used for the prevention of vascular occlusive that cause of myocardial infarction, stroke, and vascular death in patients with atherosclerosis and then it is used to ...
Titien Siwi Hartayu, Dewi Setyaningsih
doaj   +6 more sources

Ticlopidine Alone Versus Ticlopidine Plus Aspirin for Preventing Recurrent Stroke

Internal Medicine, 2003
To compare the efficacy and safety of two antiplatelet regimens, ticlopidine alone (200 mg daily) and ticlopidine (100 mg daily) plus aspirin (81 mg daily), in patients with ischemic stroke from the Tokai district of Japan.A randomized comparative study was performed from April 1992 until December 1995, with follow-up for an average of 1.59 years ...
Mitsuyoshi Nakajima, Akira Takahashi, Eiichi Ito, Shigeki Kuzuhara, Shinichiro Uchiyama, Hiroko Yamamoto   +5 more
openaire   +5 more sources

Ticlopidine-Induced Cholestatic Inflammatory Hepatitis: New Insights into Pathogenetic Mechanisms of Drug-Related Hepatotoxicity [PDF]

European Journal of Inflammation, 2006
In immune-induced liver damage the reactive metabolites may covalently bind or alter liver proteins such as cytochrome P450 enzymes, which leads to activation of the immune system. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome.
I. Kraslova, L. Muchova, L. Vitek, A. Novotny, T. Svestka, R. Bruha   +5 more
doaj   +2 more sources

Interstitial Pneumonia Induced by Ticlopidine.

Circulation Journal, 2002
A 67-year-old female non-smoker, who had been diagnosed with familial hypercholesterolemia associated with severe atherosclerosis of the coronary, carotid and vertebral arteries, developed interstitial pneumonia 4 months after initiating ticlopidine to inhibit platelet aggregation.
Takeshi Matsuo, Toshiro Nagoshi, Tetsunori Ishikawa, Masakazu Maeno, Kazuya Mishima, Ryosai Nakamura, Yoshitake Fujiura, Takuroh Imamura, Hisamitsu Onitsuka, Tanenao Eto, Haruhiko Date, Yasushi Koiwaya   +11 more
openaire   +5 more sources

Determination of ticlopidine in human plasma by capillary gas chromatography with ion trap detection [PDF]

, 2003
A gas chromatographic method for determination of ticlopidine in human plasma using mass spectrometric detection was developed. A Perkin Elmer model 8500 gas chromatograph coupled to an ion trap detector (ITD) in electron impact mode (EI) was used.
Angelina Pena, Celeste M. Lino, M.I.N. Silveira   +2 more
openalex   +4 more sources

Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting : the clopidogrel aspirin stent international cooperative study (CLASSICS). [PDF]

Circulation, 2000
M. Bertrand, H. Rupprecht, P. Urban, A. Gershlick   +3 more
semanticscholar   +2 more sources

Multivariate Adjustments for Average Equivalence Testing. [PDF]

Stat Med
ABSTRACT Multivariate (average) equivalence testing is widely used to assess whether the means of two conditions of interest are “equivalent” for different outcomes simultaneously. In pharmacological research for example, many regulatory agencies require the generic product and its brand‐name counterpart to have equivalent means both for the AUC and ...
Boulaguiem Y, Insolia L, Victoria-Feser MP, Couturier DL, Guerrier S.   +4 more
europepmc   +2 more sources

Comparative Risk of Major Bleeding With Concomitant Use of Oral Anticoagulants and Corticosteroid Bursts. [PDF]

Clin Transl Sci
ABSTRACT The choice of oral anticoagulants and oral corticosteroid (OCS) burst cotherapy may influence the risk of major bleeding; however, this risk remains poorly characterized. We aimed to quantify the comparative safety of non–vitamin K oral anticoagulants (NOACs) versus warfarin on major bleeding while receiving OCS burst cotherapy among patients ...
Yao TC, Chang SM, Tsai YF, Chiang SJ, Tsai HJ.   +4 more
europepmc   +2 more sources

Effectiveness and Safety of Reduced-Dose Prasugrel in an East Asian Population: PRASFIT-ACS Emulation Using National Health Insurance Claims Data. [PDF]

Clin Pharmacol Ther
Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Huang LW, Wu YJ, Lin FJ, Wu CC, Huang HY, Wang CC, Li X.   +6 more
europepmc   +2 more sources

APLASTIC ANAEMIA AND TICLOPIDINE [PDF]

British Journal of Haematology, 1993
Fernando Sanchez-Gil, Rafael Ramos Fdez-Soria, Eduardo Benitez-cano, Guillermo Martin-Nune   +3 more
openaire   +3 more sources