Results 21 to 30 of about 8,106 (209)

Agranulocytosis and hepatic toxicity with ticlopidine therapy: a case report

Journal of Medical Case Reports, 2010
Introduction Ticlopidine is a platelet inhibitor used to prevent thrombosis in patients with cerebrovascular or coronary artery disease. The most common side effects are mild and transitory: diarrhea, dyspepsia, nausea and rashes.
Previtera Antonino M, Pagani Rossella
doaj   +1 more source

Detecting Adverse Drug Events Through the Chronological Relationship Between the Medication Period and the Presence of Adverse Reactions From Electronic Medical Record Systems: Observational Study

JMIR Medical Informatics, 2021
BackgroundMedicines may cause various adverse reactions. An enormous amount of money and effort is spent investigating adverse drug events (ADEs) in clinical trials and postmarketing surveillance.
Kei Teramoto, Toshihiro Takeda, Naoki Mihara, Yoshie Shimai, Shirou Manabe, Shigeki Kuwata, Hiroshi Kondoh, Yasushi Matsumura   +7 more
doaj   +1 more source

THE EFFECTIVENESS OF CLOPIDOGREL AS AN ANTITHROMBOTIC COMPARED TO TICLOPIDINE AND ASPIRIN (META-ANALYSIS)

Jurnal Farmasi Sains dan Komunitas, 2017
Clopidogrel, an antithrombotic drug, has been proven by FDA as Plavix® was initially used for the prevention of vascular occlusive that cause of myocardial infarction, stroke, and vascular death in patients with atherosclerosis and then it is used to ...
Titien Siwi Hartayu, Dewi Setyaningsih
doaj   +1 more source

Pharmacokinetics of Ticlopidine in the Rabbit

Journal of Pharmacy and Pharmacology, 1999
Abstract There is no information about the pharmacokinetics of ticlopidine in rabbits. Such information is valuable in designing appropriate dosing regimens for experimental studies of the drug with ultimate applications in man. The disposition kinetics of ticlopidine at three dose levels were evaluated in three groups of six rabbits ...
Francois Vallee, Pamela R. Tessier, Cyprian O. Onyeji, Charles H. Nightingale, David P. Nicolau   +4 more
openaire   +3 more sources

Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting

Frontiers in Neurology, 2019
Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung, Suk Jae Kim, Jaechun Hwang, Mi Ji Lee, Jun Lee, Kyung-Yul Lee, Man-Seok Park, Sang Min Sung, Keon Ha Kim, Pyoung Jeon, Oh Young Bang   +10 more
doaj   +1 more source

Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2023
To reduce pharmacy-related medical expenses, it is necessary to reduce drug costs. One way to achieve this is by increasing the usage rate of generic drugs.
Takaaki Suzuki BS, Mari Iwata BS, Mika Maezawa MS, Kiyoka Matsumoto BS, Mizuki Tanaka BS, Riko Satake BS, Misaki Inoue BS, Yu Yoshida BS, Kazuhiro Iguchi PhD, Mitsuhiro Nakamura PhD   +9 more
doaj   +1 more source

Ticlopidine-induced cholestatic hepatitis: A case report and review of the literature

Italian Journal of Medicine, 2012
Introduction Cholestatic hepatitis is frequently a drug-related syndrome. We describe the case of a 57-year-old man who developed cholestatic hepatitis two months after starting therapy with ticlopidine following a carotid endarterectomy.Materials and ...
Luigi Anastasio, Valerio Manno, Maria Carbone, Nicola Lentini, Sandro Baldari, Lucia Sofia, Giuseppe Topa, Antonio Arone   +7 more
doaj   +1 more source

The effect of antiaggregational therapy on the long-term patency of the femoropopliteal/crural bypass [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2012
Introduction. Antiaggregational therapy can reduce thrombosis development following the arterial reconstruction surgery. In most cases acetylsalicylic acid and ticlopidine are used as antiaggregational agents. Objective.
Vasić Dragan, Radmili Oliver, Davidović Lazar, Vraneš Milica   +3 more
doaj   +1 more source

Antiplatelet drugs for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis

BMC Neurology, 2021
Background Antiplatelet drugs may prevent recurrent ischemic events after ischemic stroke but their relative effectiveness and harms still need to be clarified.
Cinzia Del Giovane, Giorgio B. Boncoraglio, Lorenza Bertù, Rita Banzi, Irene Tramacere   +4 more
doaj   +1 more source

The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon

Dermatology Practical & Conceptual, 2015
Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that may be complicated by Kasabach-Merritt phenomenon (KMP), a profound thrombocytopenia resulting from platelet trapping within a vascular tumor, either KHE or tufted angioma (
Grecia V. Vivas-Colmenares, Gema L. Ramirez-Villar, Jose A. Matute de Cardenas, Jose Bernabeu-Wittel, Israel Fernandez-Pineda   +4 more
doaj   +1 more source