Results 21 to 30 of about 17,756 (301)

Sensitive Voltammetric Determination of Ticlopidine in Pharmaceuticals Employing a Multi-Walled Carbon Nanotubes Paste Electrode

Orbital: The Electronic Journal of Chemistry, 2016
A sensitive analytical procedure has been developed for the determination of ticlopidine using a multi-walled carbon nanotubes paste electrode (MWCNTsPE). Direct oxidation of analyte was observed by cyclic voltammetry as evidenced by the presence of well-
Igor Rebech, Jessica Scremin, César Ricardo Teixeira Tarley, Elen Romão Sartori   +3 more
doaj   +3 more sources

Neuroborreliosis in patient with aplastic anaemia secondary to therapy with ticlopidine [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Aplastic anaemia is a rare but potentially fatal complication of treatment with ticlopidine. Case Outline. We present a 55-year-old male with aplastic anaemia which developed after 45 days of the therapy with 200 mg ticlopidine to ...
Čolović Milica, Palibrk Vuk, Vidović Ana, Čolović Nataša, Bumbaširević Ljiljana   +4 more
doaj   +1 more source

Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer

Molecules, 2022
Different pathological conditions, including viral infections and cancer, can have a massive impact on the endoplasmic reticulum (ER), causing severe damage to the cell and exacerbating the disease.
Anna Tesei, Michela Cortesi, Martina Bedeschi, Noemi Marino, Giacomo Rossino, Roberta Listro, Daniela Rossi, Pasquale Linciano, Simona Collina   +8 more
doaj   +1 more source

Ticlopidine induces cardiotoxicity in zebrafish embryos through AHR-mediated oxidative stress signaling pathway

Ecotoxicology and Environmental Safety, 2022
Ticlopidine has inhibitory effects on platelet aggregation via ADP (adenosine diphosphate), platelet release reaction and depolymerization. In clinical practice, it is commonly used to prevent heart, cerebrovascular and other thromboembolic diseases ...
Rong Xu, Yong Huang, Chen Lu, Weiming Lv, Shihua Hong, Shuqin Zeng, Wenyan Xia, Li Guo, Huiqiang Lu, Yijian Chen   +9 more
doaj  

Acyclovir Induced Acute Kidney Injury In Acute Meningitis Patient: A Case Report Highlights the Concurrence Of AKI Risk Factors And The Neutropenic Effect Of Ticlopidine [PDF]

, 2014
Nephrotoxicity is one of the challenging side effects of acyclovir use in clinical practice. The Concomitant use of other nephrotoxic antibiotics, in addition to patient's risk factors, can trigger acyclovir induced acute kidney injury (AKI).
Amin, Arwa M., Ibrahim, Baharudin, Sarriff, Azmi   +2 more
core   +1 more source

Semimechanistic Population Pharmacokinetic Model to Predict the Drug–Drug Interaction Between S‐ketamine and Ticlopidine in Healthy Human Volunteers

CPT: Pharmacometrics & Systems Pharmacology, 2018
Low‐dose oral S‐ketamine is increasingly used in chronic pain therapy, but extensive cytochrome P450 (CYP) mediated metabolism makes it prone to pharmacokinetic drug‐drug interactions (DDIs).
Muhammad W. Ashraf, Marko Peltoniemi, K. Olkkola, P. Neuvonen, Teijo I. Saari   +4 more
semanticscholar   +1 more source

Ticlopidine induces embryonic development toxicity and hepatotoxicity in zebrafish by upregulating the oxidative stress signaling pathway

Ecotoxicology and Environmental Safety, 2023
Ticlopidine exerts its anti-platelet effects mainly by antagonizing platelet p2y12 receptors. Previously, a few studies have shown that ticlopidine can induce liver injury, but the exact mechanism of hepatotoxicity remains unclear.
Rong Xu, Pengxiang Xu, Haiyan Wei, Yong Huang, Xiaodan Zhu, Chuanming Lin, Zhimin Yan, Liuyan Xin, Lin Li, Weiming Lv, Shuqin Zeng, Guiyou Tian, Jinze Ma, Bo Cheng, Huiqiang Lu, Yijian Chen   +15 more
doaj  

Results of the Ticlid or Plavix Post-Stents (TOPPS) trial: do they justify the switch from ticlopidine to clopidogrel after coronary stent placement?

Current Controlled Trials in Cardiovascular Medicine, 2000
In the Ticlid or Plavix Post-Stents (TOPPS) trial, 1016 patients undergoing successful coronary stent placement were randomized to receive aspirin and either ticlopidine or clopidogrel.
Berger Peter B
doaj   +1 more source

7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]

, 2019
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael, Gassaway, Madalee M., Grinnell, Steven G., Javitch, Jonathan A., Kruegel, Andrew C., Langreck, Cory, Le Rouzic, Valerie, Majumdar, Susruta, Pasternak, Gavril W., Pekarskaya, Elizabeth A., Pintar, John E., Sames, Dalibor, Uprety, Rajendra   +12 more
core   +3 more sources

A Paclitaxel-Eluting Stent for the Prevention of Coronary Restenosis [PDF]

, 2003
Background Intimal hyperplasia and resulting restenosis limit the efficacy of coronary stenting. We studied a coronary stent coated with the antiproliferative agent paclitaxel as a means of preventing restenosis.
Choi, D, Ho, DSW, Hong, MK, Jang, Y, Lam, R, Lee, CW, Mintz, GS, Park, SJ, Park, SW, Raizner, AE, Shim, WH, Weissman, NJ   +11 more
core   +1 more source