Results 21 to 30 of about 18,009 (296)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Integrated Genomic and GEO Data Analysis Reveals Therapeutic Targets for Rosacea. [PDF]

J Cosmet Dermatol
ABSTRACT Background Rosacea is a chronic inflammatory facial disorder with limited therapeutic options, severely impacting patients' quality of life. The identification of druggable genes plays a crucial role in facilitating the development of effective therapeutic strategies.
Deng X, He S, Long H, Xiao J, Xie Z.
europepmc   +2 more sources

Stroke following percutaneous coronary intervention : type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12 [PDF]

, 2016
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015.
Berry, Colin, British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research, Buchan, Iain, de Belder, Mark A, Keavney, Bernard, Kontopantelis, Evangelos, Kwok, Chun Shing, Ludman, Peter F, Mamas, Mamas A, Myint, Phyo K, Nolan, Jim, Zaman, Azfar   +11 more
core   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O., Diener, H. C., Glahn, J., Hamann, Gerhard F., Weimar, C.   +4 more
core   +1 more source

Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke:Pooled analysis of randomized trials [PDF]

, 2015
Background and Purpose: Lacunar stroke accounts for ≈25% of ischemic stroke, but optimal antiplatelet regimen to prevent stroke recurrence remains unclear.
Benavente, Oscar R., Copley, Hannah Charlotte, Kwok, Chun Shing, Loke, Yoon K., Myint, Phyo Kyaw, Shoamanesh, Ashkan   +5 more
core   +1 more source

Results of the Ticlid or Plavix Post-Stents (TOPPS) trial: do they justify the switch from ticlopidine to clopidogrel after coronary stent placement?

Current Controlled Trials in Cardiovascular Medicine, 2000
In the Ticlid or Plavix Post-Stents (TOPPS) trial, 1016 patients undergoing successful coronary stent placement were randomized to receive aspirin and either ticlopidine or clopidogrel.
Berger Peter B
doaj   +1 more source

7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]

, 2019
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael, Gassaway, Madalee M., Grinnell, Steven G., Javitch, Jonathan A., Kruegel, Andrew C., Langreck, Cory, Le Rouzic, Valerie, Majumdar, Susruta, Pasternak, Gavril W., Pekarskaya, Elizabeth A., Pintar, John E., Sames, Dalibor, Uprety, Rajendra   +12 more
core   +3 more sources

Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer

Molecules, 2022
Different pathological conditions, including viral infections and cancer, can have a massive impact on the endoplasmic reticulum (ER), causing severe damage to the cell and exacerbating the disease.
Anna Tesei, Michela Cortesi, Martina Bedeschi, Noemi Marino, Giacomo Rossino, Roberta Listro, Daniela Rossi, Pasquale Linciano, Simona Collina   +8 more
doaj   +1 more source

Semimechanistic Population Pharmacokinetic Model to Predict the Drug–Drug Interaction Between S‐ketamine and Ticlopidine in Healthy Human Volunteers

CPT: Pharmacometrics & Systems Pharmacology, 2018
Low‐dose oral S‐ketamine is increasingly used in chronic pain therapy, but extensive cytochrome P450 (CYP) mediated metabolism makes it prone to pharmacokinetic drug‐drug interactions (DDIs).
Muhammad W. Ashraf, Marko Peltoniemi, K. Olkkola, P. Neuvonen, Teijo I. Saari   +4 more
semanticscholar   +1 more source

Acyclovir Induced Acute Kidney Injury In Acute Meningitis Patient: A Case Report Highlights the Concurrence Of AKI Risk Factors And The Neutropenic Effect Of Ticlopidine [PDF]

, 2014
Nephrotoxicity is one of the challenging side effects of acyclovir use in clinical practice. The Concomitant use of other nephrotoxic antibiotics, in addition to patient's risk factors, can trigger acyclovir induced acute kidney injury (AKI).
Amin, Arwa M., Ibrahim, Baharudin, Sarriff, Azmi   +2 more
core   +1 more source