Results 31 to 40 of about 8,483 (184)
Is clopidogrel superior to aspirin in secondary prevention of vascular disease?
Current Controlled Trials in Cardiovascular Medicine, 2000 The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events trial ...
Algra Ale, van Gijn Jan
doaj +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2021 Hemodialysis is required for patients with end-stage renal disease (ESRD) that require arteriovenous (AV) grafts or fistulas for vascular access. These access points are prone to thrombosis. To determine the effect of medical adjuvant therapy on AV graft/
Kaleem Ullah MBBS +6 more
doaj +1 more source
Dataset of endo- and xenobiotic inhibition of CYP2B6: Comparison to CYP3A4
Data in Brief, 2022 Cytochrome P450 2B6 (CYP2B6) is a human enzyme important in chemical detoxification, steroid and fatty acid metabolism that is primarily hepatic. Therefore, induction or inhibition of CYP2B6 may perturb endo- and xenobiotic metabolism and cause adverse ...
Emily M. Olack +2 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo +22 more
wiley +1 more source
Dermatology Practical & Conceptual, 2015 Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that may be complicated by Kasabach-Merritt phenomenon (KMP), a profound thrombocytopenia resulting from platelet trapping within a vascular tumor, either KHE or tufted angioma (
Grecia V. Vivas-Colmenares +4 more
doaj +1 more source
Antinuclear Antibody-Positive Ticlopidine-Induced Hepatitis
Canadian Journal of Gastroenterology, 1996 Ticlopidine hydrochloride has been shown to reduce the risk of first or recurrent stroke in patients who have experienced a transient ischemic attack, reversible ischemic neurological deficit, recurrent stroke or first stroke. Severe liver dysfunction is
Sander Jo Veldhuyzen van Zanten +1 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Mechanisms of atherothrombosis in atherosclerosis of coronary arteries are described. Mechanism of action and clinical efficiency of antithrombotic and antiplatelet medicines such as acetylsalicylic acid, warfarin, ticlopidine and clopidogrel are ...
I. A. Latfullin, A. A. Podolskaya
doaj +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Warfarin interactions: a letter to editor [PDF]
Patient Safety and Quality Improvement Journal, 2019 Today, with the advances in the treatment of cardiovascular patients such as intravascular stents, cardiac valves and intraventricular pacing and heart transplantation, many patients require the use of anticoagulants such as warfarin, sprain, Plavix ...
Sayyed Majid Sadrzadeh +4 more
doaj +1 more source
When Delirium Unmasks a Silent Myocardial Infarction
Journal of the American Geriatrics Society, EarlyView.Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali +10 more
wiley +1 more source