Prophylaxis of Experimental Endocarditis With Antiplatelet and Antithrombin Agents: A Role for Long-term Prevention of Infective Endocarditis in Humans? [PDF]
, 2017 Background. Infective endocarditis (IE) mostly occurs after spontaneous low-grade bacteremia. Thus, IE cannot be prevented by circumstantial antibiotic prophylaxis.
Chaouch, Aziz +7 more
core
Safety of Percutaneous Muscle Biopsy: An Update Based on Over 2400 Procedures
Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 11, November 2025.ABSTRACT This study assessed the safety of percutaneous muscle biopsy by analyzing over 2400 procedures performed between 2007 and 2025 in healthy individuals and patients with chronic diseases. We retrospectively reviewed biopsy‐related adverse events among 1246 participants (471 healthy adults and 775 patients) to investigate whether health status or
Jhonnatan Vasconcelos Pereira Santos +6 more
wiley +1 more source
AGRANULOCYTOSIS AND MACULOPAPULAR RASH AFTER TREATMENT WITH TICLOPIDINE – CASE REPORT
Zdravniški Vestnik, 2003 Background. Ticlopidine is one of inhibitors of platelet aggregation indicated for reducing the risk of thrombotic stroke in patients who have experienced thrombotic stroke, ischemic attacks, unstable angina pectoris, coronary artery stenting and ...
Janja Blatnik +4 more
doaj
Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
Journal of Pharmacological Sciences, 2011 .: The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic ...
Yuichi Kinoshita +9 more
doaj +1 more source
Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool [PDF]
, 2016 Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP).
Boussery, Koen +7 more
core +1 more source
Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy
Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai +5 more
wiley +1 more source
Molecules, 2010 A methodological study devoted to the Mannich-like multicomponent synthesis of the antiplatelet agent (±)‑clopidogrel (7) and the ethyl ester analogue 6 is described.
Isabelle Aillaud +4 more
doaj +1 more source
Secondary prevention after cerebral ischaemia of presumed arterial origin: is aspirin still the touchstone? [PDF]
, 1999 Patients who have had a transient ischaemic attack or nondisabling ischaemic stroke of presumed arterial origin have an annual risk of death from all vascular causes, non-fatal stroke, or non-fatal myocardial infarction that ranges between 4% and 11%
Algra, A. (Ale) +2 more
core +2 more sources
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1695-1704, October 2025.ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed and verified for dordaviprone, a small molecule with antitumor effects in glioma patients. The model was applied to assess the drug–drug interaction (DDI) potential of dordaviprone as a victim of CYP3A4 inhibitors and inducers, and as a perpetrator of CYP3A4, CYP2C8, CYP2D6 ...
Swati Jaiswal +6 more
wiley +1 more source
Acute Iatrogenic Agranulocytosis: A Rare and Dire Case of an Adverse Drug Reaction to Be Aware
Case Reports in Hematology, 2020 Background. Iatrogenic agranulocytosis (IA), by nonchemotherapeutic drugs, is a rare adverse event, resulting in a neutrophil count under 0.5 × 109 cells/L with fever or other suggestive signs of infection. Methods.
Diogo André +5 more
doaj +1 more source