Results 31 to 40 of about 299,276 (297)
Occludin Content Modulates Hydrogen Peroxide–Induced Increase in Renal Epithelial Paracellular Permeability [PDF]
, 2015 The ability of hydrogen peroxide (H2O2) to increase paracellular permeability of renal epithelial cell monolayers was examined and the role of occludin in this regulation was investigated.
Amsler, Kurt +3 more
core +1 more source
Biochimica et biophysica acta, 1998 A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the exchange of substances between them. The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and
CITI, SANDRA, CORDENONSI, MICHELANGELO
openaire +3 more sources
Interplay between tight junctions & adherens junctions [PDF]
Experimental Cell Research, 2017 Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins.
Hannah K, Campbell +2 more
openaire +2 more sources
Claudin-2-dependent paracellular channels are dynamically gated
eLife, 2015 Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured.
Christopher R Weber +7 more
doaj +1 more source
Tight junction protein ZO-1 in Kawasaki disease
BMC Pediatrics, 2021 Background Kawasaki disease (KD) is a form of systemic febrile vasculitis that is complicated with coronary artery lesions (CAL). The tight junctions that maintain the intestinal barrier also play a role in systemic inflammatory diseases.
Wan-Tz Lai +4 more
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Current Research in Pharmacology and Drug DiscoveryIntestinal tight junction disruption contributes to the pathogenesis of inflammatory bowel diseases (IBD). We have recently reported that gallic acid was able to enhance intestinal tight junction assembly via CaMKK-β/AMPK/SIRT-1/ERK-dependent mechanisms ...
Apiwan Arinno +5 more
doaj +1 more source
PLoS ONEBackgroundTight junction abnormalities are a common feature of inflammatory skin diseases such as psoriasis and atopic dermatitis and contribute to systemic immune responses.
Kaiyi Zhou +4 more
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Biology Open, 2016 Cardiotoxicity induced by anti-cancer therapeutics is a severe, and potentially fatal, adverse reaction of the heart in response to certain drugs. Current in vitro approaches to assess cardiotoxicity have focused on analysing cardiomyocytes.
Emma L. Wilkinson +2 more
doaj +1 more source
Edge currents in frustrated Josephson junction ladders
, 2016 We present a numerical study of quasi-1D frustrated Josephson junction ladders with diagonal couplings and open boundary conditions, in the large capacitance limit.
Dias, R. G. +2 more
core +1 more source
Functional Analysis of Gastric Tight Junction Proteins in Xenopus laevis Oocytes
Membranes, 2022 The epithelial barrier is crucial for proper gastrointestinal function, preventing the unwanted passage of solutes and therefore representing a prerequisite for vectorial transport.
Laura Stein, Nora Brunner, Salah Amasheh
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