Results 21 to 30 of about 632,604 (307)
Biology Direct, 2006 Background Zonula occludens, also known as the tight junction, is a specialized cell-cell interaction characterized by membrane "kisses" between epithelial cells.
Tang Vivian W
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Nature Communications, 2017 Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction
Alexander X. Cartagena-Rivera +3 more
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Renal Failure, 2017 Tight junction plays important roles in regulating paracellular transports and maintaining cell polarity. Calcium oxalate monohydrate (COM) crystals, the major crystalline composition of kidney stones, have been demonstrated to be able to cause tight ...
Lei Yu, Xiuguo Gan, Xukun Liu, Ruihua An
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Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. [PDF]
PLoS ONE, 2017 The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and intestinal secretions, prevents passage of luminal substances and antigens through the paracellular space.
Hui Yan, Kolapo M Ajuwon
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The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density [PDF]
, 2003 Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to participate in the control of epithelial cell proliferation and differentiation.
Balda, MS +5 more
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Progress in Biophysics and Molecular Biology, 2003 A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the exchange of substances between them. The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and
L, González-Mariscal +3 more
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Tight Junctions of the Neurovascular Unit [PDF]
Frontiers in Molecular Neuroscience, 2021 The homeostatic balance of the brain and retina is maintained by the presence of the blood-brain and inner blood-retinal barrier (BBB/iBRB, respectively) which are highly specialized barriers. Endothelial cells forming the lining of these blood vessels are interconnected by the presence of tight junctions which form the BBB and iBRB.
Campbell, Matthew, Hudson, Natalie
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Wnt/beta-catenin signaling controls development of the blood–brain barrier [PDF]
, 2008 The blood–brain barrier (BBB) is confined to the endothelium of brain capillaries and is indispensable for fluid homeostasis and neuronal function. In this study, we show that endothelial Wnt/beta-catenin (beta-cat) signaling regulates induction and ...
Fruttiger, Marcus +59 more
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The mechanobiology of tight junctions [PDF]
Biophysical Reviews, 2019 Tight junctions (TJ) play a central role in the homeostasis of epithelial and endothelial tissues, by providing a semipermeable barrier to ions and solutes, by contributing to the maintenance of cell polarity, and by functioning as signaling platforms.
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Hemodynamic regulation of occludin and ZO-1: effect on barrier function [PDF]
, 2006 The vascular endothelium constitutes a highly effective fluid and solute barrier through the regulated apposition of tight junction protein complexes between adjacent endothelial cells.
Collins, Nora
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