Results 171 to 180 of about 412,031 (297)

Tricellulin regulates the tight junctions and cytoskeleton of pancreatic acinar cells through the NF-κB pathway in hypertriglyceridemic acute pancreatitis. [PDF]

Biomed Rep
Wei G, Liang Z, Wei H, Wu Q, Wang J, Lin L, Liang Z, Yang H, Qin M.   +8 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Tight junctions expression is affected by active, inactive, and derivatives of <i>Akkermansia muciniphila</i>. [PDF]

Iran J Microbiol
Ghaderi F, Hajebrahimi Z, Fateh A, Sotoodehnejadnematalahi F, Ahmadi Badi S, Vaezijoze S, Siadat SD.   +6 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Roles of protein-protein interactions and monolayer mechanics in tricellulin localization to tricellular tight junctions. [PDF]

Biol Open
Mushtaq T, Lehtimäki J, Kogan K, Peränen J, Liu X, Varjosalo M, Manninen A, Lappalainen P.   +7 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Tight Junctions [PDF]

Zeitschrift für Rheumatologie, 2016
openaire   +1 more source

Tight Junctions [PDF]

, 2012
Lorenza Gonzalez-Mariscal, Miguel Quiros, Mnica Diaz-Coranguez, Pablo Bautist   +3 more
openaire   +1 more source

Multi-Strain Probiotic and Bee Pollen Supplementation Attenuates CCl₄-Induced Altered Intestinal Tight Junctions in Rodents. [PDF]

Curr Issues Mol Biol
Alsayari N, Bhat RS, Zargar S, Aldbass AM, Al-Daihan S.   +4 more
europepmc   +1 more source