Results 71 to 80 of about 2,354,533 (305)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Recently, we reported time-resolved synchrotron small-angle X-ray scattering (TR-SAXS) studies during aqueous emulsion polymerization using a bespoke stirrable reaction cell (J. Am. Chem. Soc.2021, 143, 1474–1484).
Adam Czajka (3804124) +2 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A compact XUV beamline for temporally and spectrally resolved studies
We developed a compact XUV beamline based on High order Harmonic Generation in gases (HHG) that can be used both for time resolved studies with broadband XUV pulses and for spectrally resolved studies where individual harmonics are selected. The beamline
G. Karras +15 more
core +1 more source
High-quality total scattering data, a key tool for understanding atomic-scale structure in disordered materials, require stable instrumentation and access to high momentum transfers. This is now routine at dedicated synchrotron instrumentation using high-
Adam F. Sapnik +50 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Developments of time-resolved XAFS spectroscopy techniques – applications in homogeneous catalysis [PDF]
Catalysis is one of the most important methods to obtain products in a selective and sustainable manner, i.e. in an environmental responsible manner.
Tromp, Moniek, Tromp. Moniek
core
Highlighting radical sites through polarized neutron scattering from AFP-modulated polarized protons
Time-resolved neutron scattering has been used to study dynamically polarized protons in tyrosyl-doped bovine liver catalase. While the evolution of proton polarization and its inversion by the method of adiabatic fast passage (AFP) in a standard dynamic
Patrick Hautle +3 more
doaj +1 more source
Capturing macromolecular dynamics using time-resolved serial crystallography at X- ray free electron lasers and synchrotron light sources [PDF]
In recent years, time-resolved serial crystallography has emerged as a transformative technique for unraveling the intricate dynamics of macromolecules at atomic resolution.
Sandra Mous +28 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

