Results 71 to 80 of about 134,958 (300)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Original Approach Toward Three-Phase Indirect Matrix Converters Through Hybrid PWM Modulation and DSP Implementation

IEEE Access, 2020
Power electronic matrix converters are converters carrying out just one solitary transitional stage. AC-AC conversion automatism in matrix converters is attained through the exploitation of bidirectional controllable power switches associated with a ...
Amira Ammar, Hadi Y. Kanaan, Nazih Moubayed, Mahmoud Hamouda, Kamal Al-Haddad   +4 more
doaj   +1 more source

Sub-picosecond Resolution Time-to-Digital Converter

, 2006
Time-to-digital converters with sub-picosecond resolutions are needed to satisfy the requirements of time-on-flight measurements of the next generation of high energy and nuclear physics experiments.
Bratov, Vladimir, Katzman, Vladimir, Binkley, Jeb   +2 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Time mode analog-to-digital converter

, 2016
Fully digital Analog-to-Digital Converter (ADC) and digitally assisted ADC has gained popularity in recent research works. The continuous scaling in CMOS technology has prompted designers to look for ADC architecture that is highly digital intensive with
Hor, Hon Cheong
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

On-Chip time measurement architectures and implementation

, 2009
In recent years, system on chip (SoC) devices have become increasingly popular in many applications, such as automotive, signal processing, portable electronic devices and communication products. This has led to more functionality being integrated onto a
Collins, Matthew
core  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

High-Performance Time-to-Digital Conversion on a 16-nm Ultrascale+ FPGA

IEEE Access
In recent years, field-programmable gate arrays (FPGAs) have emerged as promising platforms for implementing picosecond-resolution time-to-digital converters (TDCs).
Lorenzo Castelvero, Ignacio H. Lopez Grande, Valerio Pruneri   +2 more
doaj   +1 more source

A Programmable Time Measurement Architecture for Embedded Memory Characterization

, 2005
This paper describes a programmable time measurement architecture that facilitates memory characterization. We have created a novel standalone time measurement architecture that can measure rise time, fall time, pulse width and propagation delay time ...
Ross, Neil, Al-Hashimi, Bashir, Collins, Matthew   +2 more
core