Results 161 to 170 of about 4,575 (215)
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Chitosan Nanoparticles for Prolonged Delivery of Timolol Maleate
Drug Development and Industrial Pharmacy, 2007Timolol maleate-loaded chitosan (CS) nanoparticles were prepared by desolvation method. Experimental variables such as molecular weight of CS and amount of crosslinking agent were varied to study their effect on drug entrapment efficiency, size and release rates of nanoparticles.
Sunil A, Agnihotri, Tejraj M, Aminabhavi
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Medical Journal of Australia, 1979
A randomized, double-masked trial of various concentrations of timolol maleate ophthalmic solution (0.1%, 0.25%, 0.5%, and 1.0%) vs placebo demonstrated that all concentrations of timolol effectively lowered intraocular pressure (IOP). A 0.5% solution of timolol was as effective in reducing IOP as the 1.0% concentration.
T J, Zimmerman +3 more
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A randomized, double-masked trial of various concentrations of timolol maleate ophthalmic solution (0.1%, 0.25%, 0.5%, and 1.0%) vs placebo demonstrated that all concentrations of timolol effectively lowered intraocular pressure (IOP). A 0.5% solution of timolol was as effective in reducing IOP as the 1.0% concentration.
T J, Zimmerman +3 more
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International Ophthalmology, 2017
To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma.This prospective, observer-masked, randomized study included 50 patients with primary open ...
Yilmaz, Suzan Guven +4 more
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To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma.This prospective, observer-masked, randomized study included 50 patients with primary open ...
Yilmaz, Suzan Guven +4 more
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Nail Pigmentation following Timolol Maleate Therapy
Ophthalmologica, 1981A 56-year-old woman with an open angle glaucoma was treated with timolol maleate topically for 6 months. The patient developed peculiar nail pigmentations of the fingers and toes which could not be related to vasospastic disorders. After withdrawal of the timolol therapy normal-colored nails grew.
V, Feiler-Ofry, V, Godel, M, Lazar
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Documenta Ophthalmologica, 2001
The objective of this study was to compare plasma concentrations of timolol following multiple dosing of the therapeutic regimens of timolol maleate ophthalmic gel-forming solution (Timolol GS; TIMOPTIC-XE) and timolol maleate ophthalmic solution. Timolol maleate ophthalmic gel-forming solution is also referred to as Timolol GS, i.e.
A H, Shedden +3 more
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The objective of this study was to compare plasma concentrations of timolol following multiple dosing of the therapeutic regimens of timolol maleate ophthalmic gel-forming solution (Timolol GS; TIMOPTIC-XE) and timolol maleate ophthalmic solution. Timolol maleate ophthalmic gel-forming solution is also referred to as Timolol GS, i.e.
A H, Shedden +3 more
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Ophthalmology, 1980
Summary Timolol maleate is a new, potent ocular antihypertensive that has an effect additive with other antiglaucoma medications. It does not cause miosis and is relatively free of ocular complications, although a few have been documented. Timolol does exacerbate asthma and should not be used in patients with a history of this disease.
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Summary Timolol maleate is a new, potent ocular antihypertensive that has an effect additive with other antiglaucoma medications. It does not cause miosis and is relatively free of ocular complications, although a few have been documented. Timolol does exacerbate asthma and should not be used in patients with a history of this disease.
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Journal Français d'Ophtalmologie, 2012
To compare systemic absorption of three formulations of timolol eye drops: 0.1% timolol maleate gel, 0.5% timolol aqueous solution, and 0.5% timolol maleate gel.This was a double cross-over phase I study. Cross-over 1: two weeks of 0.1% timolol gel once daily, followed by a 3-week wash-out period and then two weeks of 0.5% timolol aqueous solution ...
N, Bonnin +5 more
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To compare systemic absorption of three formulations of timolol eye drops: 0.1% timolol maleate gel, 0.5% timolol aqueous solution, and 0.5% timolol maleate gel.This was a double cross-over phase I study. Cross-over 1: two weeks of 0.1% timolol gel once daily, followed by a 3-week wash-out period and then two weeks of 0.5% timolol aqueous solution ...
N, Bonnin +5 more
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Differences in ocular surface irritation between timolol hemihydrate and timolol maleate
American Journal of Ophthalmology, 2000We evaluated the anterior segment surface reaction findings between timolol hemihydrate and timolol maleate. The only known difference between these preparations is the maleate salt.After a baseline examination, we randomized 28 healthy subjects (26 completed) to timolol hemihydrate or timolol maleate given in both eyes twice daily, in a double masked ...
W C, Stewart +3 more
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Topical timolol maleate might adversely affect serum lipoproteins
International Ophthalmology, 1993Conflicting observations have been reported about the effects of topically administered timolol maleate on serum lipoproteins. We therefore considered this issue in a series of eight glaucoma patients receiving timolol maleate. Cholesterol and triglycerides were measured in plasma and in low-density lipoproteins (LDL), and high-density lipoproteins ...
A B, Safran +4 more
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Timolol maleate and HDL cholesterol after myocardial infarction
European Heart Journal, 1985The influence of long-term timolol treatment on plasma lipids was analysed in cohorts of the Norwegian timolol multicentre study. The prognostic importance of high-density lipoprotein (HDL) cholesterol concentration after myocardial infarction was also examined. One year timolol treatment was related to a significant reduction in HDL cholesterol levels,
T, Gundersen +3 more
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