Results 191 to 200 of about 16,067 (252)

Targeting macrophages in liver fibrosis. [PDF]

open access: yesFront Immunol
González Del Barrio L   +4 more
europepmc   +1 more source

Association of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors with Intraventricular Haemorrhage in Preterm Infants. [PDF]

open access: yesInt J Mol Sci
Szpecht D   +9 more
europepmc   +1 more source

Engineering of Selective TIMPs

Annals of the New York Academy of Sciences, 1999
ABSTRACT: Differences in proteinase susceptibility between free TIMP‐1 and the TIMP‐1‐MMP‐3 complex and mutagenesis studies suggested that the residues around the disulfide bond between Cys1 and Cys70 in TIMP‐1 may interact with MMPs. The crystal structure of the complex between TIMP‐1 and the catalytic domain of MMP‐3 has revealed that the α‐amino ...
H, Nagase   +7 more
openaire   +2 more sources

TIMPs as multifacial proteins

Critical Reviews in Oncology/Hematology, 2004
Tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) found in most tissues and body fluids. By inhibiting MMPs activities, they participate in tissue remodeling of the extracellular matrix (ECM). The balance between MMPs and TIMPs activities is involved in both normal and pathological events such as
Elise, Lambert   +3 more
openaire   +2 more sources

Clinicopathological correlations of TIMP‐1 and TIMP‐2 in Hodgkin's lymphoma

European Journal of Haematology, 2003
Abstract:Objectives:  The influence of matrix–tumour interactions in Hodgkin's lymphoma is poorly characterised, although a large part of the tumour often consists of reactive tissue. The aim of the present study was to assess the clinicopathological role of two main inhibitors of matrix metalloproteinases, TIMP‐1 and TIMP‐2, in Hodgkin's lymphoma ...
Heli, Pennanen   +3 more
openaire   +2 more sources

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