Results 191 to 200 of about 30,124 (283)

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein, Li Xi, Rathi D. Ryan, Zhan (Harold) Ye, Nessy Tania, Yamato Sano, Joshua Varghese, Diogo Branquinho, Anna Sapone   +8 more
wiley   +1 more source

Association of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors with Intraventricular Haemorrhage in Preterm Infants. [PDF]

Int J Mol Sci
Szpecht D, Żyto K, Ciszek G, Duczmal K, Kowal Z, Kręciszewska K, Słowińska Z, Kurzawińska G, Sowińska A, Seremak-Mrozikiewicz A.   +9 more
europepmc   +1 more source

Identification of miR‐150‐5p in Human Amniotic Membrane Mesenchymal Cell‐Derived Extracellular Vesicles as a Novel Mechanism Driving Cardioprotection

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Human amniotic membrane mesenchymal stem cells (hAMSCs) provide significant cardioprotection following myocardial ischemia/reperfusion injury. They improve cardiac function and reduce fibrosis by modulating the MIAT/miR‐150‐5p/HOXA4 signalling axis.
Nunzio Alcharani, Laura Tesoro, Javier Díez‐Mata, José Luis Zamorano, Marta Saura, Maite Iglesias, Carlos Zaragoza   +6 more
wiley   +1 more source

Huanggan decoction ameliorates cholestatic hepatic fibrosis in rats via TGF-β1/Smad3 signaling pathway. [PDF]

PLoS One
Lei Y, Ma X, Jin X, He Y, Yang J, Zhao Y, Chen J, Gao T.   +7 more
europepmc   +1 more source

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

TIMP-2 as a Potential Indicator of Persistent Arthralgia in Chikungunya: Evidence From a Brazilian Cohort Study. [PDF]

J Med Virol
Costa ACS, Santos AFD, Albuquerque GCL, da Rosa MM, Taniele-Silva J, Duarte ALBP, da Rocha Pitta MG, de Siqueira AM, de Barros Albuquerque AP, de Melo Rego MJB.   +9 more
europepmc   +1 more source

Maintenance Debridement in Chronic Hard‐to‐Heal Wounds: Toward Dynamic Homeostasis and Precision Intervention

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Debridement is widely used across various wound types, but its biological significance differs fundamentally between acute and chronic hard‐to‐heal wounds. In acute wounds, debridement directly triggers the initiation of regeneration; however, in chronic wounds, persistent biofilm, insufficient angiogenesis and dysregulated inflammation lead ...
RuoDi Lu, Yi Zhang, Biao Cheng
wiley   +1 more source

The Matrisome as an Immunomodulator: A Role Far Beyond Its Structural Support. [PDF]

Biomolecules
Quan T.
europepmc   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Plasma Matrix Metalloproteinases Signature as Biomarkers for Pediatric Tuberculosis Diagnosis: A Prospective Case-Control Study. [PDF]

Diseases
Pavan Kumar N, Hissar S, Nancy A, Thiruvengadam K, Banurekha VV, Balaji S, Elilarasi S, Gomathi NS, Ganesh J, Aravind MA, Baskaran D, Swaminathan S, Babu S.   +12 more
europepmc   +1 more source