ABSTRACT Berberine (BBR) is a natural isoquinoline alkaloid with antibacterial, anti‐inflammatory and pro‐angiogenic properties. This study aimed to investigate the therapeutic efficacy and underlying mechanism of a conditioned medium (CM) derived from berberine‐preconditioned bone marrow‐derived mesenchymal stem cells (BMSCs‐BBR).
Jinglei Tan, Caiqiang Chen
wiley +1 more source
Myocardial Fibrosis in Cardiovascular Disease: An Integrative Biomarker-Imaging Framework Linking Molecular Mechanisms to Structural Phenotypes. [PDF]
Świątko M +8 more
europepmc +1 more source
Neurohumoral Biomarker Profile Associated With Blood Pressure Response After Renal Denervation
ABSTRACT Blood pressure (BP) response after renal denervation (RDN) remains heterogeneous. This study explored whether baseline neurohumoral and inflammation‐related biomarkers were associated with a pronounced ambulatory BP response after RDN. This single‐center post hoc analysis included 40 patients with uncontrolled essential hypertension who ...
Wei Liang +12 more
wiley +1 more source
Advancing Insights into Biomarkers in Congenital Anomalies of the Kidney and Urinary Tract: A Scoping Review. [PDF]
Rosanio FM +5 more
europepmc +1 more source
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source
Morphometry and Immunoexpression of Metalloproteinase 2 and Its Inhibitor in the Fibrotic and Non-Fibrotic Grafted Kidney-Digital Analysis. [PDF]
Szypulska-Koziarska D +3 more
europepmc +1 more source
The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou +6 more
wiley +1 more source
Mechanisms of Inflammation in Post-Operative Recurrence of Crohn's Disease. [PDF]
Greenwood H, Steiner CA, Click B.
europepmc +1 more source
Dupilumab attenuate IL-4 and IL-13 synergistic effect on airway remodeling in asthma via blocking IL-4Rα/STAT6 axis. [PDF]
Sahnoon L +10 more
europepmc +1 more source
Imaging and fluid biomarkers for prognostic stratification in cerebral amyloid angiopathy. [PDF]
Wang D, Lv S, Wei Y, Zhao X.
europepmc +1 more source

