Results 11 to 20 of about 4,959 (214)

Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction [PDF]

International Journal of COPD, 2017
Dimitrios Toumpanakis,1,2 Konstantinos Loverdos,1,2 Vassiliki Tzouda,1,2 Vyronia Vassilakopoulou,1,2 Eleni Litsiou,1,2 Christina Magkou,3 Vassiliki Karavana,1,2 Michael Pieper,4 Theodoros Vassilakopoulos1,2 1First Critical Care Department, Pulmonary ...
Toumpanakis D, Loverdos K, Tzouda V, Vassilakopoulou V, Litsiou E, Magkou C, Karavana V, Pieper M, Vassilakopoulos T   +8 more
doaj   +2 more sources

Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma

Frontiers in Pediatrics, 2022
Tiotropium bromide is the only long-acting muscarinic antagonist (LAMA) approved for treatment of patients aged ≥6 years old who have symptoms of uncontrolled asthma.
Francesca Santamaria, Carla Ziello, Paola Lorello, Cristina Bouchè, Melissa Borrelli   +4 more
doaj   +1 more source

Tiotropium bromide [PDF]

International Journal of COPD, 2006
Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not ...
openaire   +3 more sources

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease [PDF]

, 2010
Background Combination therapy (inhaled corticosteroids and long-acting beta(2)-agonists) and tiotropium are both used in the treatment of chronic obstructive pulmonary disease (COPD).
Appleton, Appleton, Appleton, Barr, Bateman, Calverley, Effing, Jones, Karner, Keene, Kesten, Lacasse, Nannini, Nannini, Nannini, Singh, Singh, Suissa, Suissa, Tashkin, Yang   +20 more
core   +1 more source

Efficiency of tiotropium bromide in patients with severe persistent bronchial asthma in clinical practice

Acta Biomedica Scientifica, 2018
The aim of the study was to investigate the effectiveness of tiotropium bromide in patients with severe persistent asthma under conditions of real clinical practice.
A. F. Ivanov, B. A. Chernyak
doaj   +1 more source

Effect of bronchodilator therapy on the function of external respiration and lung parenchyma in surgical treatment of patients with non-small cell lung cancer combined with chronic obstructive pulmonary disease

Сибирский онкологический журнал, 2023
The purpose of the study was to compare the efficacy of regular prolonged inhalation therapy with tiotropium bromide delivered via the Respimat inhaler and short-acting bronchodilator (SAB) therapy with ipratropium bromide/fenoterol in the perioperative ...
S. Yu. Dobner, S. V. Fedosenko, A. Yu. Dobrodeev, N. D. Yarovoy, E. N. Samtsov, А. V. Dubakov, E. A. Starovoitova, О. A. Denisova, N. A. Kirillova   +8 more
doaj   +1 more source

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]

, 2019
Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard, Kaplan, Alan, Price, David, Román-Rodríguez, Miguel, van der Molen, Thys   +4 more
core   +4 more sources

COST-MINIMIZATION OF VILANTEROL / UMECLIDINIUM VERSUS OLODATEROL / TIOTROPIUM IN THE BASIC THERAPY OF SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov, N. L. Bondarenko, A. V. Karaulov   +5 more
doaj   +1 more source

Muscarinic receptor M3 activation promotes fibrocytes contraction

Frontiers in Pharmacology, 2022
Fibrocytes are monocyte-derived cells able to differentiate into myofibroblasts-like cells. We have previously shown that they are increased in the bronchi of Chronic Obstructive Pulmonary Disease (COPD) patients and associated to worse lung function ...
Pauline Henrot, Pauline Henrot, Edmée Eyraud, Elise Maurat, Sophie Point, Guillaume Cardouat, Jean-François Quignard, Pauline Esteves, Thomas Trian, Pierre-Olivier Girodet, Pierre-Olivier Girodet, Pierre-Olivier Girodet, Roger Marthan, Roger Marthan, Maéva Zysman, Maéva Zysman, Patrick Berger, Patrick Berger, Patrick Berger, Isabelle Dupin   +19 more
doaj   +1 more source