Results 21 to 30 of about 3,023 (195)
Therapeutics and Clinical Risk Management, 2016 Ching Kuo Tan, Gui Quan Say, James B Geake Department of Respiratory Medicine, Lyell McEwin Hospital, Elizabeth Vale, SA, Australia Abstract: Tiotropium bromide is a long-acting inhaled muscarinic antagonist used in patients with chronic respiratory ...
Tan CK, Say GQ, Geake JB
doaj +1 more source
Safety and pharmacological profile of tiotropium bromide
Expert Opinion on Drug Safety, 2009 BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with progressive airflow obstruction and is characterized by a high risk of morbidity and mortality.
Pierachille Santus +3 more
core +3 more sources
Tiotropium Bromide in Children and Adolescents with Asthma.
Pediatric Drugs, 2017 Evidence is emerging on the use of long-acting muscarinic antagonists (LAMAs) in the management of asthma.
Kelly, H William, Raissy, Hengameh H
core +3 more sources
ClinicoEconomics and Outcomes Research, 2016 Abigail Tebboth,1 Andrew Ternouth,1 Nuria Gonzalez-Rojas2 1Boehringer Ingelheim Ltd., Bracknell, UK; 2Boehringer Ingelheim GmBH, Ingelheim, Germany Objective: The aim of this study is to assess the cost-effectiveness of other long-acting muscarinic ...
Tebboth A, Ternouth A, Gonzalez-Rojas N
doaj +1 more source
Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma
Frontiers in Pediatrics, 2022 Tiotropium bromide is the only long-acting muscarinic antagonist (LAMA) approved for treatment of patients aged ≥6 years old who have symptoms of uncontrolled asthma.
Francesca Santamaria +4 more
doaj +1 more source
Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers [PDF]
Clinical Drug Investigation, 2016 Jaime Algorta
exaly +2 more sources
Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning. [PDF]
Basic Clin Pharmacol ToxicolABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Pylkkö E +8 more
europepmc +2 more sources
International Journal of COPD, 2015 Anoop Prakash,1 K Suresh Babu,2 Jaymin B Morjaria1,31Department of Respiratory Medicine, Castle Hill Hospital, Cottingham, 2Department of Respiratory Medicine, Queen Alexandra Hospital, Cosham, Portsmouth, 3Department of Academic Respiratory Medicine ...
Prakash A, Babu KS, Morjaria JB
doaj +1 more source
Tiotropium bromide: an update. [PDF]
Open Respir Med J, 2009 Tiotropium bromide is a once-daily inhaled anticholinergic bronchodilator. It works by blocking the muscarinic receptors in airway smooth muscle. Tiotropium has a wide therapeutic margin, due to its poor gastrointestinal absorption and its very low systemic bioavailability. The drug is mainly indicated in COPD patients.
Heredia JL.
europepmc +4 more sources
International Journal of COPD, 2006 Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not ...
openaire +3 more sources