Results 21 to 30 of about 2,552 (169)

Characteristics of induced sputum neutrophils and macrophages in patients with chronic obstructive pulmonary disease on a basic therapy

Бюллетень сибирской медицины, 2011
Aim of the research — to define the tiotropium bromide influence on bronchial neutrophiles and macrophages morphofunctional properties at stable of chronic obstructive pulmonary disease (COPD).
S. V. Fedosenko, G. E. Chernogoryuk, N. A. Kirillova, A. Yu. Fisenko, Ye. P. Roslyakova   +4 more
doaj   +1 more source

The double bronchodilation era: new capabilities in a new drug delivery device

Медицинский совет, 2022
A literature review presents the efficacy and safety of the new glycopyrronium bromide/formoterol fumarate (GP/FF) combination in the treatment of patients with chronic obstructive pulmonary disease according to the PINNACLE 1, 2, 3, 4 studies. There are
E. A. Orlova, I. P. Dorfman, M. A. Orlov, M. A. Abdullaev   +3 more
doaj   +1 more source

The influence of basic treatment with tiotropium bromide of patients with chronic obstructive pulmonary disease stage II on the morpho-functional state of bronchial mucosa and the level of type IV collagen in bronchoalveolar lavage fluid.

Galician Medical Journal, 2018
The objective of the research was to evaluate the influence of basic treatment of patients with chronic obstructive pulmonary disease with tiotropium bromide on the processes of morphological rearrangement and local barrier defence mechanisms in the ...
Mykola Osyrovskyy, Mariana Olegivna Kulynych-Miskiv, Iryna Savelikhina, Valentina Goncharuk, Ksenia Ostrovska   +4 more
doaj   +1 more source

Pharmacoeconomic analysis of the use of a fixed combination of tiotropium bromide and olodaterol as maintenance therapy in patients with chronic obstructive pulmonary disease in the Russian Federation

Фармакоэкономика, 2022
Objective: to evaluate the pharmacoeconomic effectiveness of the use of a fixed double combination of tiotropium bromide + olodаterol in order to treat chronic obstructive pulmonary disease (COPD) in comparison with less expensive monotherapy with long ...
S. К. Zyryanov, I. N. Dyakov
doaj   +1 more source

Clinical and economic evaluation of using fixed dose dual bronchodilator combination tiotropiumolodaterol in patients with chronic obstructive pulmonary disease

Медицинский совет, 2018
The paper is devoted to the problem of clinical efficacy and pharmacoeconomic evaluation of Spiolto Respimat. The results of clinical trials prove that Spiolto Respimat in patients with COPD improves spirometric values, symptoms of dyspnea and health ...
S. K. Zyryanov, Y. A. Galatonova
doaj   +1 more source

Tiotropium/Olodaterol treatment reduces cigarette smoke extract-induced cell death in BEAS-2B bronchial epithelial cells

BMC Pharmacology and Toxicology, 2020
Background Cigarette smoking is a critical risk factor for the destruction of lung parenchyma or the development of emphysema, which is characteristic of COPD.
Cheng-hsiung Chen, Yi-Rong Li, Sheng-Hao Lin, Hsiu-Hui Chang, Woei-Horng Chai, Po-Chiang Chan, Ching-Hsiung Lin   +6 more
doaj   +1 more source

Inhaled tiotropium bromide and risk of stroke [PDF]

British Journal of Clinical Pharmacology, 2009
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Conflicting studies have raised uncertainty over the vascular effects of the long‐acting anticholinergic, tiotropium bromide. WHAT THIS STUDY ADDS • Our results show no increased risk of stroke with tiotropium bromide, or with inhaled anticholinergics in general.AIMSA recent communication from the United ...
Anthony, Grosso, Ian, Douglas, Aroon D, Hingorani, Raymond, MacAllister, Richard, Hubbard, Liam, Smeeth   +5 more
openaire   +2 more sources

Skin reaction to inhaled tiotropium bromide: a case report

Journal of Medical Case Reports, 2011
Introduction Systemic reactions to inhaled drugs are rare. To the best of our knowledge, we report the first case of generalized itching related to the use of tiotropium bromide, a long acting inhaled anti-cholinergic agent commonly used to treat chronic
Megali Raffaella, Fuiano Nicola, Incorvaia Cristoforo, Riario-Sforza Gian   +3 more
doaj   +1 more source

Analisis Efektivitas Biaya Terapi Tiotropium Bromide Dibandingkan dengan Salmeterol/Fluticasone Propionate pada Pasien Penyakit Paru Obstruktif Kronik (PPOK) di RSUD Tabanan

JPSCR: Journal of Pharmaceutical Science and Clinical Research
Penyakit paru obstruktif kronik (PPOK) merupakan penyakit progresif yang membutuhkan terapi jangka panjang dengan bronkodilator. Dua terapi yang banyak digunakan adalah golongan long-acting muscarinic antagonists (LAMA) yaitu Tiotropium Bromide (Spiriva®)
Sagung Chandra Yowani, Yayanasri Yayanasri, Rasmaya Niruri, Rini Noviyani   +3 more
doaj   +1 more source

Therapy and control of bronchial asthma in children and adolescents

Медицинский совет, 2020
Up to 22% of the population in the world suffer from bronchial asthma according to the data from different regions and sources. This is about 358 million people.
T. N. Surovenko, E. F. Glushkova
doaj   +1 more source