Results 11 to 20 of about 3,023 (195)

Inhibition of granulocyte migration by tiotropium bromide [PDF]

Respiratory Research, 2011
Study objectives Neutrophil influx into the airways is an important mechanism in the pathophysiology of the inflammatory process in the airways of patients with chronic obstructive pulmonary disease (COPD).
Randerath Winfried J, Vacca Gabriela, Gillissen Adrian   +2 more
doaj   +4 more sources

Frequency of Tiotropium Bromide Use and Clinical Features of Patients with Severe Asthma in a Real-Life Setting: Data from the Severe Asthma Network in Italy (SANI) Registry. [PDF]

J Asthma Allergy, 2020
Frequency of Tiotropium Bromide Use and Clinical Features of Patients with Severe Asthma in a Real-Life Setting: Data from the Severe Asthma Network in Italy (SANI ...
Puggioni F, Brussino L, Canonica GW, Blasi F, Paggiaro P, Caminati M, Latorre M, Heffler E, Senna G, Severe Asthma Network in Italy (SANI) group.   +9 more
europepmc   +2 more sources

Suppression of IL-8 production from airway cells by tiotropium bromide in vitro

International Journal of COPD, 2011
Isao Suzaki1, Kazuhito Asano2, Yusuke Shikama3, Taisuke Hamasaki1, Ayako Kanei1, Harumi Suzaki11Department of Otorhinolaryngology, School of Medicine, Showa University, Tokyo, Japan; 2Division of Physiology, School of Nursing and Rehabilitation Sciences,
Suzaki I, Asano K, Shikama Y, Hamasaki T, Kanei A, Suzaki H   +5 more
doaj   +1 more source

Pharmacological characterization of the interaction between tiotropium bromide and olodaterol on human bronchi and small airways

Pulmonary Pharmacology and Therapeutics, 2019
Combining a long-acting beta(2)-agonist (LABA) with a long-acting muscarinic antagonist (LAMA) is the cornerstone to treat patients with chronic obstructive pulmonary disease (COPD).
Luigino Calzetta, Paola Rogliani, Clive P Page   +2 more
exaly   +2 more sources

Inhaled tiotropium bromide and risk of stroke. [PDF]

British Journal of Clinical Pharmacology, 2009
AIMS: A recent communication from the United States Food and Drug Administration highlighted a possible increased risk of stroke associated with use of the relatively new inhaled anticholinergic drug, tiotropium bromide.
Hubbard, Richard, Richard Hubbard, Smeeth, Liam, Douglas, Ian, MacAllister, Raymond, Hingorani, Aroon D, Raymond MacAllister, Grosso, Anthony, Ian Douglas, Aroon D. Hingorani, Anthony Grosso, Liam Smeeth   +11 more
core   +3 more sources

Ten years of tiotropium: clinical impact and patient perspectives

International Journal of COPD, 2013
Abebaw M Yohannes,1 Martin J Connolly,2 Nicola A Hanania31Manchester Metropolitan University, Department of Health Professions, Manchester, UK; 2University of Auckland, Freemasons’ Department of Geriatric Medicine, Auckland, New Zealand ...
Yohannes AM, Connolly MJ, Hanania NA
doaj   +1 more source

Tiotropium bromide, a long acting muscarinic receptor antagonist triggers intracellular calcium signalling in the heart [PDF]

Toxicology and Applied Pharmacology, 2019
Background and purpose: Tiotropium bromide (TB) is a long acting muscarinic receptor antagonist used to manage chronic obstructive pulmonary disease (COPD). Recent meta-analyses suggest an increased risk of cardiovascular events with TB.
Shabana Cassambai, Derek Renshaw, Afthab Hussain   +2 more
exaly   +2 more sources

Skin reaction to inhaled tiotropium bromide: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Systemic reactions to inhaled drugs are rare. To the best of our knowledge, we report the first case of generalized itching related to the use of tiotropium bromide, a long acting inhaled anti-cholinergic agent commonly used to treat chronic
Megali Raffaella, Fuiano Nicola, Incorvaia Cristoforo, Riario-Sforza Gian   +3 more
doaj   +3 more sources

Tiotropium: a new therapeutic option in asthma

Monaldi Archives for Chest Disease, 2013
Tiotropium: a new therapeutic option in asthma. F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro. Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic ...
F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro   +6 more
doaj   +3 more sources

Safety, tolerability and risk benefit analysis of tiotropium in COPD

International Journal of COPD, 2008
Yuji Oba, Tareq Zaza, Danish M ThameemUniversity of Missouri, School of Medicine, Division of Pulmonary, Critical Care and Environmental Medicine, Columbia, MO, USAAbstract: COPD is a chronic disease and, like many other chronic diseases, there is no ...
Yuji Oba, Tareq Zaza, Danish M Thameem
doaj   +1 more source