Results 31 to 40 of about 3,023 (195)

Effect of bronchodilator therapy on the function of external respiration and lung parenchyma in surgical treatment of patients with non-small cell lung cancer combined with chronic obstructive pulmonary disease

Сибирский онкологический журнал, 2023
The purpose of the study was to compare the efficacy of regular prolonged inhalation therapy with tiotropium bromide delivered via the Respimat inhaler and short-acting bronchodilator (SAB) therapy with ipratropium bromide/fenoterol in the perioperative ...
S. Yu. Dobner, S. V. Fedosenko, A. Yu. Dobrodeev, N. D. Yarovoy, E. N. Samtsov, А. V. Dubakov, E. A. Starovoitova, О. A. Denisova, N. A. Kirillova   +8 more
doaj   +1 more source

Muscarinic receptor M3 activation promotes fibrocytes contraction

Frontiers in Pharmacology, 2022
Fibrocytes are monocyte-derived cells able to differentiate into myofibroblasts-like cells. We have previously shown that they are increased in the bronchi of Chronic Obstructive Pulmonary Disease (COPD) patients and associated to worse lung function ...
Pauline Henrot, Pauline Henrot, Edmée Eyraud, Elise Maurat, Sophie Point, Guillaume Cardouat, Jean-François Quignard, Pauline Esteves, Thomas Trian, Pierre-Olivier Girodet, Pierre-Olivier Girodet, Pierre-Olivier Girodet, Roger Marthan, Roger Marthan, Maéva Zysman, Maéva Zysman, Patrick Berger, Patrick Berger, Patrick Berger, Isabelle Dupin   +19 more
doaj   +1 more source

Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. [PDF]

, 2011
BACKGROUND: The long-term efficacy and safety of aclidinium bromide, a novel, long-acting muscarinic antagonist, were investigated in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
Fabbri, Leonardo M., Caracta, C, Stephen I Rennard, James F Donohue, Caracta, Cynthia, Gil, Esther Garcia, Jones, PW, Donohue, JF, Magnussen, Helgo, Bateman, ED, Nicholas J Gross, Bateman, Eric D, Channez, Pascal, Fabbri, L, Agusti, Alvar, Lamarca R, Gross Nicholas J, Magnussen Helgo, Gil, Esther G, Cynthia Caracta, Caracta Cynthia, Chanez P, Jones, Paul, Agusti Alvar, Paul W Jones, Lamarca, R, Bateman, Eric D., Jones, Paul W., Gross, Nicholas J, Esther Garcia Gil, Agusti A, Gil, Esther, Rosa Lamarca, Alvar Agusti, Jones, Paul W, Chanez, P, Fabbri Leonardo, Magnussen H, Helgo Magnussen, Donohue JF, Gil, EG, Magnussen, H, Donohue James F, Gross, Nicholas J., Garcia Gil, Esther, Jones PW, Rennard, SI, Lamarca, Rosa, Gross NJ, Agusti, A, Caracta C, Eric D Bateman, Jones Paul W, Gil Esther, Chanez, Pascal, Donohue, James F, Donohue, James F., Bateman Eric D, Rennard, Stephen I., Bateman, Eric, Rennard Stephen I, Gross, Nicholas, Gross, NJ, Pascal Chanez, Rennard, Stephen, Bateman ED, Agustí García-Navarro, Àlvar, Lamarca Rosa, Chanez Pascal, Rennard, Stephen I, Rennard SI, Gil EG, Fabbri, Leonardo, Leonardo Fabbri, Donohue, James   +74 more
core   +1 more source

COST-MINIMIZATION OF VILANTEROL / UMECLIDINIUM VERSUS OLODATEROL / TIOTROPIUM IN THE BASIC THERAPY OF SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov, N. L. Bondarenko, A. V. Karaulov   +5 more
doaj   +1 more source

The interaction of tiotropium with long lasting β2-agonists on lung cell function [PDF]

, 2013
The major question addressed in this thesis was to find the mechanism(s) by which muscarinic receptors interact with β2-adrenergic receptors in human airway fibroblasts.
Costa, Luigi
core   +1 more source

The evidence on tiotropium bromide in asthma: from the rationale to the bedside. [PDF]

Multidiscip Respir Med, 2017
Severe and poorly controlled asthma still accounts for a great portion of the patients affected. Disease control and future risk management have been identified by international guidelines as the main goals in patients with asthma. The need for new treatment approaches has led to reconsider anticholinergic drugs as an option for asthma treatment ...
Radovanovic D, Santus P, Blasi F, Mantero M.   +3 more
europepmc   +6 more sources

COST-EFFECTIVENESS OF VILANEROL / UMECLIDINIUM VERSUS TIOTROPIUM IN SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
In accordance with currently accepted recommendations for the diagnosis and treatment of chronic obstructive pulmonary disease (COPD), both monotherapy with long-acting anticholinergics (LAAC) or combined therapy (LAAC / long-acting beta-agonists, LABA ...
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov   +3 more
doaj   +1 more source

Characteristics of induced sputum neutrophils and macrophages in patients with chronic obstructive pulmonary disease on a basic therapy

Бюллетень сибирской медицины, 2011
Aim of the research — to define the tiotropium bromide influence on bronchial neutrophiles and macrophages morphofunctional properties at stable of chronic obstructive pulmonary disease (COPD).
S. V. Fedosenko, G. E. Chernogoryuk, N. A. Kirillova, A. Yu. Fisenko, Ye. P. Roslyakova   +4 more
doaj   +1 more source

The double bronchodilation era: new capabilities in a new drug delivery device

Медицинский совет, 2022
A literature review presents the efficacy and safety of the new glycopyrronium bromide/formoterol fumarate (GP/FF) combination in the treatment of patients with chronic obstructive pulmonary disease according to the PINNACLE 1, 2, 3, 4 studies. There are
E. A. Orlova, I. P. Dorfman, M. A. Orlov, M. A. Abdullaev   +3 more
doaj   +1 more source

The influence of basic treatment with tiotropium bromide of patients with chronic obstructive pulmonary disease stage II on the morpho-functional state of bronchial mucosa and the level of type IV collagen in bronchoalveolar lavage fluid.

Galician Medical Journal, 2018
The objective of the research was to evaluate the influence of basic treatment of patients with chronic obstructive pulmonary disease with tiotropium bromide on the processes of morphological rearrangement and local barrier defence mechanisms in the ...
Mykola Osyrovskyy, Mariana Olegivna Kulynych-Miskiv, Iryna Savelikhina, Valentina Goncharuk, Ksenia Ostrovska   +4 more
doaj   +1 more source