Results 11 to 20 of about 177,664 (273)
Rat perivascular adipose tissue microvasculature revealed by tissue clearing [PDF]
Frontiers in PhysiologyPerivascular adipose tissue (PVAT) surrounds the majority of blood vessels and plays diverse roles in vascular and metabolic functions. The hormonal and lipid exchange functions of PVAT require access to blood vessels.
Stephanie W. Watts +3 more
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Aqueous-based tissue clearing in crustaceans [PDF]
Zoological Letters, 2018 Background Investigation of the internal tissues and organs of a macroscopic organism usually requires destructive processes, such as dissection or sectioning. These processes are inevitably associated with the loss of some spatial information. Recently,
Alu Konno, Shigetoshi Okazaki
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Optimizing tissue-clearing conditions based on analysis of the critical factors affecting tissue-clearing procedures [PDF]
Scientific Reports, 2018 Tissue-clearing techniques have received great attention for volume imaging and for the potential to be applied in optical diagnosis. In principle, tissue clearing is achieved by reducing light scattering through a combination of lipid removal, size ...
June Hoan Kim +8 more
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Nat Rev Methods Primers, 2021 Tissue clearing of gross anatomical samples was first described over a century ago and has only recently found widespread use in the field of microscopy. This renaissance has been driven by the application of modern knowledge of optical physics and chemical engineering to the development of robust and reproducible clearing techniques, the arrival of ...
Richardson DS +7 more
europepmc +6 more sources
Method for tissue clearing: temporal tissue optical clearing. [PDF]
Biomed Opt Express, 2022 Light absorption and scattering in biological tissue are significant variables in optical imaging technologies and regulating them enhances optical imaging quality. Optical clearing methods can decrease light scattering and improve optical imaging quality to some extent but owing to their limited efficacy and the potential influence of optical clearing
Shariati B K B +5 more
europepmc +3 more sources
See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules [PDF]
International Neurourology Journal, 2016 Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues.
Eunsoo Lee, Hyun Jung Kim, Woong Sun
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Methods and Protocols, 2021 Organic solvent dibenzyl ether (DBE)-based protocols have been widely used in adipose tissue clearing. However, benzyl alcohol/benzyl benzoate (BABB)-based clearing has been shown to offer better transparency in other tissues.
Quyen Vi Luong +4 more
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Clarifying Tissue Clearing [PDF]
Cell, 2015 Biological specimens are intrinsically three dimensional; however, because of the obscuring effects of light scatter, imaging deep into a tissue volume is problematic. Although efforts to eliminate the scatter by "clearing" the tissue have been ongoing for over a century, there have been a large number of recent innovations.
Richardson, Douglas S. +1 more
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CLARITY techniques based tissue clearing: types and differences
Folia Morphologica, 2022 CLARITY is a tissue imaging technique that uses hydrogel embedded tissue to remove lipids while maintaining the intactness of protein and tissue fine structure.
Z. Guo, Y. Zheng, Y. Zhang
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NeuroImage, 2022 The accessibility of new wide-scale multimodal imaging techniques led to numerous clearing techniques emerging over the last decade. However, clearing mesoscopic-sized blocks of aged human brain tissue remains an extremely challenging task.
Henriette Rusch +8 more
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