Results 91 to 100 of about 6,889,134 (415)
Temperature Effects on Brain Tissue in Compression [PDF]
Journal of the Mechanical Behavior of Biomedical Materials, 14
(2012) 113-118, 2013 Extensive research has been carried out for at least 50 years to understand the mechanical properties of brain tissue in order to understand the mechanisms of traumatic brain injury (TBI). The observed large variability in experimental results may be due to the inhomogeneous nature of brain tissue and to the broad range of test conditions.
arxiv +1 more source
A mechanistic approach to design smart scaffolds for tissue engineering [PDF]
, 2006 This thesis describes a library of novel 3D scaffolds designed and optimized for tissue engineering and regenerative medicine applications. Tissue engineering aims at restoring or regenerating a deamaged tissue by combining cells, derived from a patient ...
Moroni, Lorenzo
core +1 more source
Bioadditive manufacturing of hybrid tissue scaffolds for controlled release kinetics [PDF]
, 2012 Development of engineered tissue scaffolds with superior control over cell-protein interactions is still very much infancy. Advancing through heterogeneous multifold scaffolds with controlled release fashion enables synchronization of regenerating tissue
Khoda, AKMB +2 more
core +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Multi-Compartmental Biomaterial Scaffolds for Patterning Neural Tissue Organoids in Models of Neurodevelopment and Tissue Regeneration [PDF]
J. Tissue Engineering 2016; 7:1-8, 2016 Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional (3D) culture of stem cells, and, more recently, also enable high-resolution patterning and organization of multicellular architectures.
arxiv +1 more source
Calcium‐sensing receptor‐ and ADAM10‐mediated klotho shedding is regulated by tetraspanin 5
FEBS Letters, Volume 599, Issue 6, Page 866-875, March 2025.The G protein‐coupled calcium‐sensing receptor (CaSR) and the disintegrin/metalloprotease ADAM10 in the renal distal convoluted tubule control systemic levels of Klotho, a cell and tissue homeostasis‐preserving factor. We show that CaSR‐induced cleavage of membrane‐bound αKlotho by ADAM10 requires tetraspanin 5 (Tspan5), a scaffolding and chaperone ...
Zhenan Liu +4 more
wiley +1 more source
Strain stiffening universality in composite hydrogels and soft tissues [PDF]
arXiv, 2023 Soft biological tissues exhibit a remarkable resilience to large mechanical loads, a property which is associated with the strain stiffening capability of the biopolymer networks that structurally support the tissues. Yet, recent studies have shown that composite systems such as tissues and blood clots exhibit mechanical properties that contradict ...
arxiv
Composite guidance scaffolds for neural tissue engineering [PDF]
, 2004 No abstract ...
Phillips, James
core
Human colon organoid differentiation from induced pluripotent stem cells using an improved method
FEBS Letters, Volume 599, Issue 6, Page 912-924, March 2025.We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee +4 more
wiley +1 more source
Automated Design of Tissue Engineering Scaffolds by Advanced CAD [PDF]
, 2007 The design of scaffolds with an intricate and controlled internal structure represents a challenge for Tissue Engineering. Several scaffold manufacturing techniques allow the creation of complex and random architectures, but have little or no control ...
Harris, R. A., Ramin, E.
core +1 more source