Results 61 to 70 of about 6,285,517 (352)

Tissue engineering; strategies, tissues, and biomaterials

open access: yesBiotechnology and Genetic Engineering Reviews, 2017
Current tissue regenerative strategies rely mainly on tissue repair by transplantation of the synthetic/natural implants. However, limitations of the existing strategies have increased the demand for tissue engineering approaches. Appropriate cell source, effective cell modification, and proper supportive matrices are three bases of tissue engineering.
Bakhshandeh, Behnaz   +6 more
openaire   +4 more sources

An ex vivo human cartilage repair model to evaluate the potency of a cartilage cell transplant

open access: yesJournal of Translational Medicine, 2016
Background Cell-based therapies such as autologous chondrocyte implantation are promising therapeutic approaches to treat cartilage defects to prevent further cartilage degeneration.
Christoph Bartz   +5 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Biopolymers for Tissue Engineering [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2014
A brief overview of the biopolymers used for cell and tissue engineering is presented. The results of research of matrices made from resorbable polyhydroxyalkanoates with different composition in fibroblast cell line culture are ...
Elena D. Nikolaeva
doaj  

Spider Silk for Tissue Engineering Applications

open access: yesMolecules, 2020
Due to its properties, such as biodegradability, low density, excellent biocompatibility and unique mechanics, spider silk has been used as a natural biomaterial for a myriad of applications.
S. Salehi, K. Koeck, T. Scheibel
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Engineering multifunctional bioactive citrate-based biomaterials for tissue engineering

open access: yesBioactive Materials, 2023
Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine. Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile ...
Min Wang, Peng Xu, Bo Lei
doaj  

Supramolecular Biopolymers for Tissue Engineering

open access: yesAdvances in Polymer Technology, 2021
Supramolecular biopolymers (SBPs) are those polymeric units derived from macromolecules that can assemble with each other by noncovalent interactions.
Rosario Pérez-Pedroza   +4 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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