Results 131 to 140 of about 18,027,656 (296)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Correction: Hydrogel Based on Adipose Tissue-Derived Extracellular Matrix Encapsulated with Microspheres Containing Epidermal Growth Factor (EGF) and Vascular Endothelial Growth Factor (VEGF) Accelerate Diabetic Wound Healing in a Rat Model [PDF]

Abdullah Alghamdi, Mohammed Alissa, Mohammed A. Alshehri   +2 more
openalex   +1 more source

Subepithelial connective tissue graft with and without the use of plasma rich in growth factors for treating root exposure [PDF]

, 2012
Ardeshir Lafzi, Masoumeh Faramarzi, Adileh Shirmohammadi, Ahmad Behrozian, Atabak Kashefimehr, Ehsan Khashabi   +5 more
openalex   +1 more source

Data from Associations between Etiologic or Prognostic Tumor Tissue Markers and Neighborhood Contextual Factors in Male Health Professionals Diagnosed with Prostate Cancer

, 2023
Hari S. Iyer, Kevin H. Kensler, Jane B. Vaselkiv, Konrad H. Stopsack, Charlotte Roscoe, Elisa V. Bandera, Bo Qin, Thomas L. Jang, Tamara L. Lotan, Peter James, Jaime E. Hart, Lorelei A. Mucci, Francine Laden, Timothy R. Rebbeck   +13 more
openalex   +1 more source

Phase II study of dacarbazine given with modern prophylactic anti-emetics and growth factor support to patients with metastatic, resistant soft tissue, and bone sarcoma [PDF]

, 2021
Brian A. Van Tine, Mia C. Weiss, Angela C. Hirbe, Peter Oppelt, Sarah Abaricia, Kathryn Trinkaus, Jingqin Luo, Shellie Berry, Tyler Ruff, Cheryl Callahan, Jacqui Toensikoetter, Jessica Ley, Marilyn J. Siegel, Farrokh Dehdashti, Barry A. Siegel, Douglas R. Adkins   +15 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Recombinant Factor VIII SQ—Stability of VIII: C in Homogenates from Porcine, Monkey and Human Subcutaneous Tissue [PDF]

, 2000
Angelica Fatouros, Ylva Lidén, Brita Sjöström   +2 more
openalex   +1 more source

RISK FACTORS ASSOCIATED WITH IN-HOSPITAL MORTALITY AND PREDICTING OUTCOMES IN SEVERE ACUTE COMPOSITE TISSUE INJURIES

, 2023
A. M. Naimov, A.A. RAZZOKOV, F.M. PARPIEV   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Factors Influencing Long-Term Local Recurrence, Distant Metastasis, and Survival in Patients with Soft Tissue Sarcoma of the Extremities Treated with Radiotherapy [PDF]

A. Lebas, Clara Le Fèvre, Waïsse Waïssi, Isabelle Chambrelant, David Brinkert, G. Noël   +5 more
openalex   +1 more source