Results 21 to 30 of about 1,251,677 (333)

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

open access: yes, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
A Bianchini   +60 more
core   +13 more sources

Tissue Factor Pathway Inhibitors as Potential Targets for Understanding the Pathophysiology of Preeclampsia

open access: yesBiomedicines, 2023
Background: Preeclampsia is a hypertensive disorder of pregnancy that causes maternal and perinatal morbidity and mortality worldwide. Preeclampsia is associated with complex abnormalities of the coagulation and fibrinolytic system. Tissue factor (TF) is
Hiroshi Kobayashi   +4 more
doaj   +1 more source

Tissue factor pathway inhibitor for prediction of placenta-mediated adverse pregnancy outcomes in high-risk women: AngioPred study. [PDF]

open access: yesPLoS ONE, 2017
OBJECTIVE:The study aimed to evaluate if the rate of tissue factor pathway inhibitor during pregnancy and following delivery could be a predictive factor for placenta-mediated adverse pregnancy outcomes in high-risk women.
Aurélie Di Bartolomeo   +6 more
doaj   +1 more source

Biology of tissue factor pathway inhibitor

open access: greenBlood, 2014
Jeremy P. Wood   +3 more
openalex   +2 more sources

Propofol promotes angiogenesis in rats with postmenopausal osteoporosis [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate the impact of propofol on angiogenesis in postmenopausal osteoporosis (PMOP) rats and the role of Wnt/β-catenin signal pathway in this process. Methods Female Wistar rats were randomly grouped into sham operation group,
ZHAO Xiaoqi, DONG Xin, LIU Cong, REN Pengcheng, ZHANG Liang
doaj   +1 more source

Expression of tissue factor and tissue factor pathway inhibitors during ovulation in rats: a relevance to the ovarian hyperstimulation syndrome

open access: yesReproductive Biology and Endocrinology, 2021
Background Blood coagulation has been associated with ovulation and female infertility. In this study, the expression of the tissue factor system was examined during ovulation in immature rats; the correlation between tissue factor and ovarian ...
You Jee Jang   +6 more
doaj   +1 more source

Tissue Factor Pathway Inhibitor Gene Disruption Produces Intrauterine Lethality in Mice [PDF]

open access: bronzeBlood, 1997
Zhong-Fu Huang   +3 more
openalex   +2 more sources

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]

open access: yes, 2012
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone   +2 more
core   +2 more sources

Heparanase and Coagulation–New Insights

open access: yesRambam Maimonides Medical Journal, 2014
Heparanase, a β-D-endoglucuronidase abundant in platelets that was discovered 30 years ago, is an enzyme that cleaves heparan sulfate side chains on the cell surface and in the extracellular matrix. It was later recognized as being a pro-inflammatory and
Yona Nadir
doaj   +1 more source

Heparanase—A Link between Coagulation, Angiogenesis, and Cancer

open access: yesRambam Maimonides Medical Journal, 2012
Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner.
Yona Nadir, Benjamin Brenner
doaj   +1 more source

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