Results 181 to 190 of about 97,283 (253)

Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2.

Mol Ther, 2017
Wang H, Zhang H, Sun Q, Wang Y, Yang J, Yang J, Zhang T, Luo S, Wang L, Jiang Y, Zeng C, Cai D, Bai X.   +12 more
europepmc   +1 more source

Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic. [PDF]

Connect Tissue Res, 2014
Stetler-Stevenson WG, Gavil NV.
europepmc   +1 more source

Spatial Mismatch Between Angiographic Obstruction and Plaque Destabilization in Acute Coronary Syndromes: A Conceptual Narrative Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The identification of the “culprit lesion” in acute coronary syndromes (ACS) traditionally relies on coronary angiography, assuming that the most severe stenosis, abrupt occlusion, or largest filling defect marks the site of plaque destabilization.
Fernando Quevedo‐Candela, Olivier F. Bertrand, Pedro Cepas‐Guillén, Jean‐Pierre Déry, David García‐Labbé, Andrés Ruhl, Eduardo Flores‐Umanzor, Tomas Cieza   +7 more
wiley   +1 more source

Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis. [PDF]

Crit Care Med, 2016
Honore PM, Nguyen HB, Gong M, Chawla LS, Bagshaw SM, Artigas A, Shi J, Joannes-Boyau O, Vincent JL, Kellum JA, Sapphire and Topaz Investigators.   +10 more
europepmc   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Effects of Phospholipase A₂ and Metalloproteinase Inhibitors on Skeletal Muscle Regeneration After Myonecrosis Induced by the Venom of <i>Bothrops asper</i>: An Initial Assessment in Mice. [PDF]

Toxins (Basel)
Zamora A, Rucavado A, Escalante T, Gutiérrez JM, Camacho E.   +4 more
europepmc   +1 more source

Diagnostic Value of Urine Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Acute Kidney Injury: A Meta-Analysis. [PDF]

PLoS One, 2017
Su Y, Gong Z, Wu Y, Tian Y, Liao X.
europepmc   +1 more source

Microbiome and Tumor Microenvironment Interactions: Advances From Ecological Niches to Precision Oncology

Cancer Nexus, EarlyView.
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang, Ji'an Liu, Jing Li, Xue Liu, Yang Su, Peng Luo, Yuhan Zhang, Zhengrui Li   +7 more
wiley   +1 more source

Unraveling the Multimodal Oncogenic Network of KITENIN: From Metabolic Reprogramming and Microenvironment Remodeling to Targeted Interventions

Cancer Nexus, EarlyView.
ABSTRACT KAI1 C‐terminal interacting tetraspanin (KITENIN) is an emerging oncogenic regulator associated with tumorigenesis, metastasis, therapeutic resistance, and poor clinical outcomes. Mechanistically, KITENIN promotes tumor cell proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT) by activating oncogenic pathways ...
Niaz Mahmood Tanoy, Zarin Tasnim, Md Shiblee Sadik Sabuj, Tanvir Ahmed, Md Abdul Momin, Md Sadekuzzaman, Sumaia Islam Mow, Md Aktaruzzaman, Md Rashedunnabi Akanda   +8 more
wiley   +1 more source

A protein-small molecule conjugate as a bispecific inhibitor of proteases implicated in cancer metastasis. [PDF]

Sci Rep
Bahat I, Pinkert Y, Baumann A, Arbely E, Miller AK, Papo N.   +5 more
europepmc   +1 more source