Results 31 to 40 of about 155,119 (260)

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F., Gilles, Stefanie, Sommerhoff, Christian P., Welsch, Ulrich, Zahler, Stefan   +4 more
core   +1 more source

IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway

Stem Cells International, 2018
Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear.
Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang   +5 more
doaj   +1 more source

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun, Acar, Göksemin, Demir, R., Tanriover, G.   +3 more
core   +1 more source

Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon [PDF]

, 2006
To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue inhibitors of metalloproteinases (TIMPs), and ADAM genes 8, 10, 12, and 17 in normal, painful, and ruptured ...
Alfredson, Alfredson, Amour, Amour, Anthony N. Corps, Archambault, Arnoczky, Asakura, Astrom, Baker, BenEzra, Bjur, Black, Brew, Brian L. Hazleman, Caroline J. Pennington, Cawston, Clancy, Conover, Dickinson, Drummond, Dylan R. Edwards, Fenwick, Gavin C. Jones, Graham P. Riley, Hannafin, Hashimoto, Hieta, Ian M. Clark, Iba, Iba, Ireland, Jarvinen, Jones, Jozsa, Kannus, Kashiwagi, Kashiwagi, Killar, Kurisaki, Lavagnino, Lo, Loechel, Ma, Majima, Malfait, Michelle M. Bradley, Movin, Mueller, Muller, Nakamura, Nuttall, Pei, Pendas, Porter, Primakoff, Rees, Riley, Riley, Riley, Roy, Sandy, Sandy, Sedlacek, Somerville, Sternlicht, Thodeti, Tipton, Tsuzaki, Van Meurs, Van Meurs, Velasco, Yasuda, Yu   +73 more
core   +1 more source

The role of proteases in pathologies of the synovial joint [PDF]

, 2008
Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost frictionless surface for articulation.
Buttle, D, Jones, GC, Riley, GP
core   +1 more source

Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling [PDF]

, 2012
Tissue inhibitor of metalloproteinases 1 (TIMP-1) is a matrix metalloproteinase (MMP)-independent regulator of growth and apoptosis in various cell types.
Avalos, Bartel, Behrens, Brew, C. Ries, Chirco, Clevers, Dasse, Day, Egea, Fata, Goff, Guedez, Guo, Huang, Huang, Ivey, Jho, Jiang, John, Joyce, Jung, K. Kehe, Liu, M. Jochum, MacDonald, Martinez, N. Rieth, P. Neth, Peter, Pittenger, Prockop, Reynolds, S. Zahler, Schiltz, Shtutman, Singer, T. Popp, Takahashi, Taube, V. Egea, Wingfield, Yi   +42 more
core   +1 more source

Inhibitory antibodies designed for matrix metalloproteinase modulation [PDF]

, 2019
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Fischer, Thomas, Riedl, Rainer
core   +1 more source

Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population

BMJ Open Diabetes Research & Care, 2020
IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila, Chernov, Andrei V, Dolkas, Jennifer, Hullugundi, Swathi K, Remacle, Albert G, Shubayev, Veronica I, Strongin, Alex Y   +6 more
core   +2 more sources

Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion

Endocrine Oncology
Objective: To evaluate the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) in pituitary tumors and investigate their correlation with circulating plasma proteins and cavernous sinus invasion ...
Ane Caroline Thé B Freire, Raquel S Jallad, Rafael L Batista, Andrea Glezer, Marcio C Machado, Gilberto Ochman, Valter A Cescato, Malebranche Berardo Carneiro Cunha Neto, Fernando P Frassetto, Raphael S S de Medeiros, Ericka B Trarbach   +10 more
doaj   +1 more source