Results 31 to 40 of about 97,464 (112)

Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients

Journal of Dental Sciences, 2016
Background/purpose: Matrix metalloproteinases (MMPs) and tissue inhibitor of MMPs (TIMPs) have been shown to play an important role in the pathogenesis of tissue destruction in periodontitis. The associations between single nucleotide polymorphisms (SNPs)
Yu-Feng Hsiao, Li-Chiu Yang, Yu-Shian Chou, Ya-Ping Ho, Ying-Chu Lin, Kun-Yen Ho, Yi-Min Wu, Chi-Cheng Tsai   +7 more
doaj   +1 more source

Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.

Folia Histochemica et Cytobiologica, 2011
The aim of the study was to assess the importance of the measurement of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of matrix metalloproteinases 2 (TIMP-2) in patients with colorectal cancer (CRC) in relation to clinicopathological features ...
Barbara Mroczko, Magdalena Groblewska, Mariusz Gryko, Bogusław Kędra, Maciej Szmitkowski   +4 more
doaj   +1 more source

Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways

Antioxidants, 2020
Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and tissue remodeling. The present study aimed to investigate the effects of cigarette smoke extract (CSE) on matrix metalloproteinase (MMP) and tissue inhibitor of ...
Joo-Hoo Park, Jae-Min Shin, Hyun-Woo Yang, Tae Hoon Kim, Seung Hoon Lee, Heung-Man Lee, Jae-Gu Cho, Il-Ho Park   +7 more
doaj   +1 more source

PECULIARITIES OF THE FIBROSIS AND CIRRHOSIS MONITORING AMONG CHILDREN WITH CHRONIC LIVER DISEASES

Педиатрическая фармакология, 2009
The researchers examined the opportunities to use determination in the serum among children with chronic liver diseases of various etiologies of the hyaluronic acid levels, collagen type IV, matrix metalloproteinase-2, tissue inhibitor of the matrix ...
A.N. Surkov, I.E. Smirnov, A.S. Potapov, A.G. Kucherenko, E.L. Tumanova   +4 more
doaj   +2 more sources

Effects of Curcumin against Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor Metalloproteinase-2 (TIMP-2) Serum Level on Rat Model of Liver Fibrosis Resolution Process

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2018
Background: Liver fibrosis is an effect from continuous fibrogenesis and fibrolysis process. During fibrogenesis, MMP-2 and TIMP-2 that produced by hepatic stellate cell (HSC) have a role to regulate extracellular matrix (ECM) homeostastic.
Supriono, Bogi Pratomo, Muhammad Kriestian   +2 more
doaj   +1 more source

Urinary matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 biomarkers for predicting renal scar in children with urinary tract infection

Urology Research and Practice, 2019
Objective: Urinary tract infection occurs in 1.8–6.6% of children under 6 years old. The aim of this study was to assess the urinary concentrations of matrix metalloproteinase 9 (MMP9) and tissue inhibitor of metalloproteinase 1 (TIMP1), in children with
Seyed Mohammad Abedi, Hamid Mohammadjafari, Alireza Rafiei, Sara Bazi, Pooneh Yazdani   +4 more
doaj   +1 more source

Temporal Patterns of 14 Blood Biomarker candidates of Cardiac Remodeling in Relation to Prognosis of Patients With Chronic Heart Failure—The Bio‐SHiFT Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Remodeling biomarkers carry high potential for predicting adverse events in chronic heart failure (CHF) patients. However, temporal patterns during the course of CHF, and especially the trajectory before an adverse event, are unknown.
Elke Bouwens, Milos Brankovic, Henk Mouthaan, Sara Baart, Dimitris Rizopoulos, Nick van Boven, Kadir Caliskan, Olivier Manintveld, Tjeerd Germans, Jan van Ramshorst, Victor Umans, K. Martijn Akkerhuis, Isabella Kardys   +12 more
doaj   +1 more source

Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling

Frontiers in Immunology, 2018
Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Taro Yasuma, Kota Nishihama, Atsuro Takeshita, Hajime Fujimoto, Mizuho Nagao, Takao Fujisawa, Esteban C. Gabazza   +10 more
doaj   +1 more source

Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date.
Sayantan Jana, Hao Zhang, Gary D. Lopaschuk, Darren H. Freed, Consolato Sergi, Paul F. Kantor, Gavin Y. Oudit, Zamaneh Kassiri   +7 more
doaj   +1 more source

Circulating interleukin-6 (IL-6) levels are associated with aortic dimensions in genetic aortic conditions.

PLoS ONE, 2019
BackgroundBiomarkers that reflect progression of dilatation of the aorta in patients with aortic conditions are needed as surrogate tools to assist in monitoring the condition in a non-invasive manner in combination with imaging procedures.
Daishi Fujita, Liliana Preiss, Kenichi Aizawa, Federico Asch, Kim Eagle, Toru Suzuki, GenTAC registry investigators   +6 more
doaj   +1 more source