Results 231 to 240 of about 122,684 (358)

MicroRNA-221 promotes proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) by targeting tissue inhibitor of metalloproteinases-3 (TIMP3). [PDF]

Cardiovasc Diagn Ther, 2020
Yan Y, Xu Y, Ni G, Wang S, Li X, Gao J, Zhang H.   +6 more
europepmc   +1 more source

The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases [PDF]

, 1992
Gillian Murphy, Frances Willenbrock, Robin V. Ward, Mark I. Cockett, Diane Eaton, Andrew Docherty   +5 more
openalex   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs. [PDF]

Eur J Histochem
Yuan J, Li L, Fan Y, Xu X, Huang X, Shi J, Zhang C, Shi L, Wang Y.   +8 more
europepmc   +1 more source

The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family.

, 1996
Suneel Apte, Bjørn R. Olsen, Gillian Murphy   +2 more
openalex   +1 more source

Circulating Total and Active Metalloproteinase‐9 and Tissue Inhibitor of Metalloproteinases‐1 in Patients with Systemic Lupus Erythomatosus [PDF]

, 2006
Ewa Robak, Agnieszka Wierzbowska, Magdalena Chmiela, Lilianna Kulczycka, Anna Sysa-Jędrejowska, Tadeusz Robak   +5 more
openalex   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Risk Factors Association with Transcriptional Activity of Metalloproteinase 9 (MMP-9) and Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Genes in Patients with Heart Failure. [PDF]

Biomedicines
Dąbek J, Korzeń D, Sierka O, Paluszkiewicz L, Milting H, Gąsior Z.   +5 more
europepmc   +1 more source

Serum Proteomic Signatures of Rheumatoid Arthritis Risk and Response: Analysis of a Rheumatoid Arthritis Interception Trial

Arthritis &Rheumatology, EarlyView.
Objective Our study objective was to identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA (Arthritis Prevention In the Preclinical Phase of RA with Abatacept) study participants were selected from baseline to RA ...
Marianna Jasenecova, Carl Coyle, Alina Mihalovits, Sarah Ryan, Elizabeth Pook, Esperanza Perucha, Gabrielle Harker, Melody Chin, Sam Norton, Andrew P. Cope   +9 more
wiley   +1 more source

Rhein Inhibits Integrin-Linked Kinase Expression and Regulates Matrix Metalloproteinase-9/Tissue Inhibitor of Metalloproteinase-1 Ratio in High Glucose-Induced Epithelial-Mesenchymal Transition of Renal Tubular Cell

, 2012
Linlin Peng, Jiayi Yang, Ning Chen, Jing Zhang, Xiangcheng Xiao, Dan He, Xiaoyuan Wang, Zhiping Li, Shuangshuang Fu, Jianping Ning   +9 more
openalex   +2 more sources