Results 251 to 260 of about 166,094,829 (292)
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Immunolocalization of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human subconjunctival tissues

Current Eye Research, 1998
To evaluate the roles of fibroblast proteins in the remodeling of the subconjunctival connective tissue, we immunohistochemically assessed the expression of matrix metalloproteinases (MMP)-1 and -2, and the tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2 in cultured human subconjunctival fibroblasts and in normal and healing human ...
Y, Kawashima   +5 more
openaire   +2 more sources

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

Journal of Cellular Physiology, 1994
AbstractMatrix proteases play a critical role in cell invasion and migration, including the process of angiogenesis. The ability of specific factors to induce angiogenic responses correlates with their stimulation of matrix protease synthesis and release.
M D, Johnson   +5 more
openaire   +2 more sources

Response of plasma matrix metalloproteinases and tissue inhibitor of metalloproteinases to stent-graft surgery for descending thoracic aortic aneurysms [PDF]

open access: yesJournal of Thoracic and Cardiovascular Surgery, 2007
ObjectiveThe role of matrix metalloproteinases and their tissue endogenous inhibitors has been documented in abdominal aortic aneurysms, but few articles have investigated their role after thoracic aortic aneurysm treatment.
Gabriele Iannelli   +2 more
exaly   +2 more sources

Tissue inhibitor of metalloproteinases‐3 is the major metalloproteinase inhibitor in the decidualizing murine uterus

Molecular Reproduction and Development, 1996
Embryo implantation in the mouse is a highly orchestrated process, a key aspect of which is the invasion of trophoblast cells of the blastocyst into the maternal uterine endometrium. Invasion is facilitated via proteinases expressed by trophoblast cells and balanced by expression of inhibitors of proteinases in the maternal decidua.
Leco, K J, Edwards, D R, Schultz, G A
openaire   +2 more sources

Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in kidney disease

2021
Matrix metalloproteinases (MMPs) are a group of zinc and calcium endopeptidases which cleave extracellular matrix (ECM) proteins. They are also involved in the degradation of cell surface components and regulate multiple cellular processes, cell to cell interactions, cell proliferation, and cell signaling pathways.
Oskar, Zakiyanov   +3 more
openaire   +2 more sources

Tissue inhibitors of metalloproteinases in liver fibrosis

The International Journal of Biochemistry & Cell Biology, 1997
Liver fibrosis and its end stage sequelae cirrhosis represent a major worldwide health problem. By definition progressive fibrosis occurs when the rate of matrix synthesis exceeds matrix degradation. Considerable evidence suggests that the hepatic stellate cell is central to the fibrotic process.
openaire   +2 more sources

Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma

Journal of Surgical Oncology, 2010
AbstractBackground and ObjectivesMatrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs).
Ming, Zhang   +4 more
openaire   +2 more sources

Matrix metalloproteinases and their tissue inhibitors in endocrinology

Trends in Endocrinology & Metabolism, 1996
Matrix metalloproteinases (MMPs) and their natural inhibitors (TIMPs) have been widely implicated in tissue resorption, degradation, and fibrosis in a range of normal and abnormal processes, but recently defined additional actions suggest much broader and independent roles for different members of these gene families.
openaire   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Sera and Tissue of Patients with Dupuytren’s Disease

Plastic and Reconstructive Surgery, 2003
Dupuytren's contracture is a fibroproliferative disorder characterized by progressive deposition of mature collagen fibers. In other fibrotic diseases affecting organs such as the liver, lung, heart, and skin, matrix metalloproteinases (MMPs) and their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), play an important role.
Dietmar, Ulrich   +2 more
openaire   +2 more sources

Quantification of matrix metalloproteinases and tissue inhibitors of metalloproteinase in prostatic tissue: Analytical aspects

The Prostate, 1998
The balance between matrix metalloproteinases (MMP) and the tissue inhibitors of metalloproteinases (TIMP) has been seen as important during tumor invasion and progression. The determination of these components needs a special strategy of tissue preparation.
K, Jung   +6 more
openaire   +2 more sources

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