Results 11 to 20 of about 166,146,473 (295)

Matrix metalloproteinases and their specific tissue inhibitors in menstruation [PDF]

open access: yesReproduction, 2002
Abstract The timely breakdown of extracellular matrix is essential for menstruation. Matrix metalloproteinases, which are able to degrade virtually all components of the extracellular matrix, are spatiotemporally expressed in the cyclic endometrium.
Dong JC, Dong H, Campana A, Bischof P
openaire   +4 more sources

Matrix metalloproteinases and their inhibitors [PDF]

open access: yesФармакокинетика и Фармакодинамика, 2019
Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich   +2 more
doaj   +2 more sources

Modulation of plasma matrix metalloproteinase 9 and its inhibitors by vitamin D. [PDF]

open access: yes, 2012
PhDMatrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are upregulated in a variety of diseases. Hypothesis: As TIMP-1 levels are elevated in liver fibrosis, might a similar process occur in essential hypertension driven left ...
Timms, Peter McLean
core   +4 more sources

Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]

open access: yes, 2009
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Braun, Thomas   +11 more
core   +2 more sources

Serum levels of matrix metalloproteinases-2 and-9 and their tissue inhibitors in inflammatory neuromuscular disorders [PDF]

open access: yes, 2006
We monitored serum levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) before and during intravenously applied immunoglobulin (IVIG) therapy in 33 patients with chronic immune-mediated neuropathies and myopathies and 15 ...
Mueller-Felber, W.   +3 more
core   +1 more source

Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease

open access: yesHeart International, 2009
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross   +7 more
doaj   +1 more source

Biochemical markers assessing rate of reparative processes in patients with infiltrative pulmonary tuberculosis

open access: yesИнфекция и иммунитет, 2023
Theeffectiveness of chemotherapy for infiltrative pulmonary tuberculosis (ITL) is determined by proper timing and adequacy of treatment. The speed of reparative changes in the pulmonary parenchyma is associated with the effectiveness of therapy ...
Dilyara S. Esmedlyaeva   +2 more
doaj   +1 more source

Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors [PDF]

open access: yesJournal of Biological Chemistry, 2007
The sarafotoxins and endothelins are approximately 25-residue peptides that spontaneously fold into a defined tertiary structure with specific pairing of four cysteines into two disulfide bonds. Their structures show an interesting topological similarity to the core of the metalloproteinase interaction sites of the tissue inhibitors of ...
Janelle L, Lauer-Fields   +5 more
openaire   +2 more sources

Exogenously added GPI-anchored tissue inhibitor of matrix metal loproteinase-1 (TIMP-1) displays enhanced and novel biological activities [PDF]

open access: yes, 2004
The family of tissue inhibitors of metalloproteinases (TIMPs) exhibits diverse physiological/biological functions including the inhibition of active matrix metalloproteinases, regulation of proMMP activation, cell growth, and the modulation of ...
P.J. Nelson   +9 more
core   +1 more source

The possibilities of using the inhibitors of matrix metalloproteinases for keratoplasty

open access: yesТрансплантология (Москва), 2023
Introduction. The review is devoted to the actual problem of treating patients with keratolysis. The role of matrix metalloproteinases in the pathogenesis of cornea and corneal graft melting is discussed as well as the practical experience of using ...
K. V. Sirotkina, E. V. Chentsova
doaj   +1 more source

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